Results 161 to 170 of about 7,354 (190)

Correction: <i>BAG3</i>-related myofibrillar myopathy: focus on its cardiac involvement. [PDF]

Front Genet
Daire E, Panaioli E, Gitiaux C, Gardin C, Waldmann V, Bonnet D, Wahbi K, Khraiche D.   +7 more
europepmc   +1 more source

Small bites for big problems: stepwise aggregate degradation by autophagy. [PDF]

Biochem Soc Trans
Hipp MS, Mauthe M.
europepmc   +1 more source

TDP-43 skein-like inclusions are formed by BAG3- and HSP70-guided co-aggregation with actin binding proteins [PDF]

Nat Cell Biol
In multiple neurodegenerative diseases, the RNA-binding protein TDP-43 forms cytoplasmic aggregates of distinct morphologies, including skein-like, small rounded granular and large spherical inclusions.
Shan Lu, Sitao Zhang, Spencer Oung, J. Diedrich, Peng Han, Olatz Arnold-García, Takuya Ohkubo, O. A. Arogundade, Sonia Vazquez-Sanchez, Ke Zhang, J. Ravits, John R. Yates, Don W. Cleveland   +12 more
semanticscholar   +2 more sources

BAG3-related myofibrillar myopathy: focus on its cardiac involvement [PDF]

Front Genet
Myofibrillar myopathy is a cause of rare and severe pediatric cardiomyopathies. Few descriptions of patients carrying the rare p. Pro209Leu variant in BAG3 and presenting with myofibrillar myopathy are reported in the literature.
Elise Daire, E. Panaioli, Cyril Gitiaux, Catherine Gardin, Victor Waldmann, Damien Bonnet, K. Wahbi, D. Khraiche   +7 more
semanticscholar   +2 more sources

Unraveling the Role of BAG3 in Hepatic Fibrosis: Genetic and Biomarker Insights in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) [PDF]

Int J Mol Sci
Metabolic dysfunction-associated steatotic liver disease (MASLD) represents a major global health burden, with hepatic fibrosis being the strongest determinant of clinical outcomes.
B. M. Motta, Alessandra Rosati, M. Festa, A. Basile, T. Sarcina, M. C. Turco, Marcello Persico   +6 more
semanticscholar   +2 more sources

HSPB1 silencing enhances ferroptosis in glioma cells by suppressing BAG3 expression. [PDF]

Am J Transl Res
OBJECTIVES To investigate the role of heat shock protein family B (small) member 1 (HSPB1) in regulating ferroptosis in glioma and to explore the underlying molecular mechanisms. METHODS HSPB1 expression was analyzed in glioma cell lines.
Qin Li, Hong-Gang Ma, Zi Ye, L. Huo
semanticscholar   +2 more sources

The multiple activities of BAG3 protein: Mechanisms

Biochimica Et Biophysica Acta - General Subjects, 2020
Background: BAG3 was identified as a co-chaperone of the heat shock protein (Hsp) 70, which helps, through the binding to the ATPase domain, the ADP release from the chaperone and the nucleotide cycling.
Liberato Marzullo, Maria Caterina Turco, Margot De Marco   +2 more
exaly   +2 more sources

BAG3: a multifaceted protein that regulates major cell pathways

Cell Death and Disease, 2011
Bcl2-associated athanogene 3 (BAG3) protein is a member of BAG family of co-chaperones that interacts with the ATPase domain of the heat shock protein (Hsp) 70 through BAG domain (110-124 amino acids).
Alessandra Rosati, Vincenzo Graziano, Vincenzo De Laurenzi   +2 more
exaly   +2 more sources

BAG3 controls angiogenesis through regulation of ERK phosphorylation [PDF]

Oncogene, 2012
BAG3 is a co-chaperone of the heat shock protein (Hsp) 70, is expressed in many cell types upon cell stress, however, its expression is constitutive in many tumours.
Alessandra Rosati, Vincenzo De Laurenzi, Antonio Barbieri   +2 more
exaly   +2 more sources

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METTL3-mediated m6A modification of circCSDE1 promote Coxsackievirus replication by regulating the miR-891b/BAG3 axis.

International Immunopharmacology
Coxsackievirus (CV), a major etiological agent of pediatric hand-foot-mouth disease and viral myocarditis, exploits host epigenetic mechanisms to facilitate pathogenesis.
Lulu Wang, Hua Wang, Tingjun Liu, Xiao-Xiang Zhou, Shou-Gang Kuai, Zeng-Jun Ji, Hong-Xing Shen   +6 more
semanticscholar   +1 more source