Results 21 to 30 of about 3,071 (129)

Regulating survival and development in the retina: key roles for simple sphingolipids

open access: yesJournal of Lipid Research, 2010
Many sphingolipids have key functions in the regulation of crucial cellular processes. Ceramide (Cer) and sphingosine (Sph) induce growth arrest and cell death in multiple situations of cellular stress. On the contrary, sphingosine-1-phosphate (S1P), the
Nora P. Rotstein   +3 more
doaj   +1 more source

Unique thermal behavior of sphingomyelin species with nonhydroxy and 2-hydroxy very-long-chain (C28-C32) PUFAs

open access: yesJournal of Lipid Research, 2013
In rat germ cells and spermatozoa, sphingomyelin (SM) contains molecular species with nonhydroxy (n) and 2-hydroxy (h) very-long-chain polyunsaturated fatty acids (V), the most abundant being SMs with (n- and h-) 28:4n-6, 30:5n-6, and 32:5n-6 as acyl ...
Daniel A. Peñalva   +4 more
doaj   +1 more source

Lipids at the Crossroad of α-Synuclein Function and Dysfunction: Biological and Pathological Implications

open access: yesFrontiers in Cellular Neuroscience, 2019
Since its discovery, the study of the biological role of α-synuclein and its pathological implications has been the subject of increasing interest. The propensity to adopt different conformational states governing its aggregation and fibrillation makes ...
Natalia P. Alza   +8 more
doaj   +1 more source

The endocannabinoid system in the visual process

open access: yesJournal of Photochemistry and Photobiology, 2023
An increasing number of articles have been published in recent years on the role of the endocannabinoid system (ECS) in different cellular processes. Here we review and discuss findings on the ECS in visual processing and present the structure of the ...
Susana J. Pasquaré   +2 more
doaj   +1 more source

La oferta de microcréditos en Argentina:¿un obstáculo o una oportunidad?

open access: yesRevista de Estudios Cooperativos, 2020
El mercado de microcréditos (MC) de Argentina presenta un bajo desarrollo, comparado con sus países vecinos. Esta situación, si bien puede verse como un problema o un obstáculo, también representa una oportunidad para crecer. Al indagar sobre las causas
María Agustina Tauro   +2 more
doaj   +1 more source

Regulation of nicotinic acetylcholine receptors by post-translational modifications

open access: yesPharmacological Research, 2023
Nicotinic acetylcholine receptors (nAChRs) comprise a family of pentameric ligand-gated ion channels widely distributed in the central and peripheric nervous system and in non-neuronal cells. nAChRs are involved in chemical synapses and are key actors in
Juan Facundo Chrestia   +5 more
doaj   +1 more source

Climate‐Modulated Particle Toxicity: Acute Exposure to an Environmentally Informed Microplastic Mixture Induces Sex‐Dependent Systemic Reorganization in Swiss Mice

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Microplastic (MP) pollution is widely recognized as an emerging environmental threat. Yet, most studies still rely on controlled experimental conditions that poorly reflect environmental complexity, potentially underestimating risks under realistic scenarios, particularly during short‐term exposures. Here, we tested whether acute oral exposure
Guilherme Malafaia   +5 more
wiley   +1 more source

The Embryonic Development of the Cotylean Polyclad Phrikoceros jannetae

open access: yesActa Zoologica, EarlyView.
ABSTRACT Polyclads exhibit distinct developmental modes ranging from direct to indirect development, with several transitional stages also recognised. The existence of an indirect developmental mode in polyclads with a planktonic life history stage in the form of a free‐swimming larva is unique among all free‐living flatworms and makes polyclads a ...
Mehrez Gammoudi   +6 more
wiley   +1 more source

New insights on neurodegeneration triggered by iron accumulation: Intersections with neutral lipid metabolism, ferroptosis, and motor impairment

open access: yesRedox Biology
Brain iron accumulation constitutes a pathognomonic indicator in several neurodegenerative disorders. Metal accumulation associated with dopaminergic neuronal death has been documented in Parkinson's disease.
Athina Maniscalchi   +9 more
doaj   +1 more source

Nodular Lesions in the Pyloric Caeca of Sardinella aurita (Teleostei) Associated With the Cestode Anthobothrium sp. 1 Larvae (Platyhelminthes: Eucestoda) Off Tunisia, Mediterranean Sea

open access: yesJournal of Fish Diseases, EarlyView.
ABSTRACT Examination of round sardinella Sardinella aurita Valenciennes, 1847 (Clupeidae) from the Gulf of Tunis (Tunisia) revealed the first local and Mediterranean record of Anthobothrium sp. 1 sensu Jensen & Bullard, 2010 (Tetraphyllidea incertae sedis, Anthobothrium).
Chiraz Ben Saad   +6 more
wiley   +1 more source

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