Results 131 to 140 of about 9,549 (183)

Baicalin protects retinal ganglion cells by regulating microglial polarization and ferroptosis via the JAK2/STAT3 pathway. [PDF]

Front Pharmacol
Yu H, Xu T, Feng Q, Wang Y, Zou J, Ma X.
europepmc   +1 more source

Baicalin modulates metabolic and inflammatory proteins and attenuates neuronal damage in a rat model of ischemic stroke. [PDF]

J Vet Sci
Son HK, Park DJ, Kim HH, Kang JB, Koh PO.   +4 more
europepmc   +1 more source

The Role of Traditional Chinese Medicine in Metabolic Reprogramming, Tumor microenvironment, and Macrophage Regulation: Mechanisms and Advances in Preclinical Studies. [PDF]

J Cancer
Yu A, Yang D, Chen H.
europepmc   +1 more source

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Baicalin, a natural LSD1 inhibitor

Bioorganic Chemistry, 2016
Baicalin is one of the active ingredients in the skullcap, with a variety of pharmacological effects, such as blood pressure reduction, sedation, liver-protection, gallbladder-protection, anti-bacteria, and anti-inflammation. In our study, baicalin was first characterized as a LSD1 inhibitor with an IC50 of 3.01μM and showed strong LSD1 inhibitory ...
Hong-Min Liu, Yi-Chao Zheng, Bin Yu
exaly   +3 more sources

Microbial transformation of baicalin and baicalein

Journal of Molecular Catalysis B: Enzymatic, 2007
As a result of microbial transformation of baicalin and baicalein the products of 4′-hydroxylation of the B ring, O-methylation at C-6, and both O-methylation at C-6 and hydroxylation at C-4′ were obtained. Transformations of baicalin were accompanied by the reaction of hydrolysis.
Jan Oszmiański, Edyta Kostrzewa-Susłow, Jadwiga Dmochowska-Gładysz   +2 more
exaly   +3 more sources

Baicalin and lung diseases

Naunyn-Schmiedeberg's Archives of Pharmacology, 2023
Studies focusing on natural products have been conducted worldwide, and the results suggest that their natural ingredients effectively treat a wide range of illnesses. Baicalin (BIA) is a glycoside derived from the flavonoid baicalein present in Scutellaria baicalensis of the Lamiaceae family.
Zeina W, Sharawi, Islam M, Ibrahim, Esraa K, Abd-Alhameed, Hanan S, Althagafy, Fatima A, Jaber, Steve, Harakeh, Emad H M, Hassanein   +6 more
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Electrochemical investigations of baicalin and DNA?baicalin interactions

Analytical and Bioanalytical Chemistry, 2004
Baicalin is an anti-HIV drug purified from the traditional Chinese medicinal plant Scutellaria Baicalensis Georgi. Baicalin has proven to be electroactive at pyrolytic graphite (PG) electrodes. We thus studied its interaction with DNA via the electrochemical approach. We observed that the peak currents corresponding to the baicalin reduction-oxidation (
Ziyi, Sun, Zhong, Ma, Wenjun, Zhang, Xiaoyue, Wang, Chunhai, Fan, Genxi, Li   +5 more
openaire   +2 more sources

Synthesis of baicalin-copper and baicalin-aluminium complex and its bioactivity

China Journal of Chinese Materia Medica, 2012
Objective To study synthesis of baicalin-copper and baicalin-aluminium complex and its antimicrobial, anti-tumor activity and anti-tumor effect against macrophages. Method Baicalin was reacted with metallic salt under a weak base condition to produce baicalin-copper and baicalin-aluminium complex.
Yanji, Liu, Xiaoyan, He, Xiaohua, Liu, Hua, Zuo, Zhubo, Li, Zonghui, Wu, Chunyan, Xiang, Xiangyu, Lai   +7 more
openaire   +3 more sources