Results 111 to 120 of about 11,830 (227)

Baicalin attenuates PD-1/PD-L1 axis-induced immunosuppression in piglets challenged with Glaesserella parasuis by inhibiting the PI3K/Akt/mTOR and RAS/MEK/ERK signalling pathways

Veterinary Research
Infection of piglets with Glaesserella parasuis (G. parasuis) induces host immunosuppression. However, the mechanism underlying the immunosuppression of piglets remains unclear.
Shulin Fu, Jingyang Li, Jiarui You, Siyu Liu, Qiaoli Dong, Yunjian Fu, Ronghui Luo, Yamin Sun, Xinyue Tian, Wei Liu, Jingyi Zhang, Yu Ding, Yitian Zhang, Wutao Wang, Ling Guo, Yinsheng Qiu   +15 more
doaj   +1 more source

Effect of amine functionalization of SBA-15 on controlled baicalin drug release

, 2012
In this paper, we present the release of baicalin from hexagonal periodic mesoporous silica SBA-15 and amino-functionalized mesoporous SBA-15 (A-SBA-15), which serve as drug delivery systems (SBA-15/baicalin and A-SBA-15/baicalin).
Wang, Yanan, Gao, Xiaohan, Niu, Xiaodi, Deng, Xuliang, Wang, Hongsu, Wang, Jianfeng   +5 more
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Inhibitory Effect of Baicalin and Baicalein on Ovarian Cancer Cells [PDF]

, 2013
Ovarian cancer is one of the primary causes of death for women all through the Western world. Baicalin and baicalein are naturally occurring flavonoids that are found in the roots and leaves of some Chinese medicinal plants and are thought to have ...
Li, Zhaoliang, Jianchu Chen, Yi Chen, Rankin, Gary O, Chen, Allen Y, Xingqian Ye, Haitao Luo, Chen, Jianchu, Luo, Haitao, Zhaoliang Li, Allen Chen, Gary Rankin, Chen, Yi C, Ye, Xingqian   +13 more
core   +1 more source

Metabolism of glycyrrhizin and baicalin by human intestinal bacteria

, 1996
By human intestinal bacteria, glycyrrhizin (18β-glycyrrhetic acid β-D-glucuronyl α-D-glucuronic acid, GL) and baicalin (baicalein β-D-glucuronic acid) were metabolized to glycyrrhetinic acid and baicalin, respectively.
Kyeu-Yup Lee, Il-Sung Jang, Dong-Hyun Kim, Eun-Ah Jung, Hyeong Kyu Lee   +4 more
core   +1 more source

Baicalin reduces inflammation to inhibit lung cancer via targeting SOCS1/NF-κB/STAT3 axis

Heliyon
Inflammation affects several aspects of lung cancer progression including cell proliferation, metastasis, apoptosis, angiogenesis, and drug resistance.
Lijuan Guo, Ming Yue, Chengyuan Ma, Yunjing Wang, Jiejie Hou, Hong Li   +5 more
doaj   +1 more source

Baicalin Ameliorates Imiquimod-Induced Psoriasis-Like Inflammation in Mice

, 2018
Baicalin is the main flavonoid from the roots of an important medicinal plant, Scutellaria baicalensis, which shows a variety biological activities. Psoriasis is a chronic immune-mediated inflammatory disease that affects the skin.
Jia Jiang, Jiunn-Wang Liao, Chien-Neng Wang, Chien-Hui Hung, Ya-Wen Chao, Huei-Hsuan Cheng, Chen-Chen Lee, Yi-Ting Chen   +7 more
core   +1 more source

Baicalin alleviates lead-induced cognitive dysfunction by modulating apoptosis and autophagy in mice

Ecotoxicology and Environmental Safety
Lead exposure is a well-documented environmental neurotoxin that poses a persistent threat to brain development. Excessive lead accumulation in this region impairs cognitive function and induces neuronal damage, yet effective therapeutic interventions ...
Jia Yu, Dahai Yu, Yong Pang, Weiyun Zhang, Shuang Liu, Xuexun Fang, Jie Zhang   +6 more
doaj   +1 more source

Antihyperglycemic Effects of Baicalin on Streptozotocin – Nicotinamide induced Diabetic Rats

, 2011
The aim of the study was to investigate the effects of baicalin on blood glucose, insulin and cytokine levels. Rat diabetes was induced by intraperitoneal (i.p.) injection of nicotinamide and streptozotocin. Diabetic rats were dosed with i.p. baicalin or
Wu, XD, Li, Huan-Ting, Davey, A.K., Wang, J., K. Davey, Andrew, Xiao-Dong Wu, Li, H.T., Jiping Wang, Li, HT, Wang, J, Wu, X.D., Wang, Jiping, Andrew K. Davey, Wu, Xiao-Dong, Huan-Ting Li, Davey, AK   +15 more
core   +1 more source

Identifying iron-binding antioxidants in New Zealand honeydew honey [PDF]

, 2013
Iron is an essential element for human physiological function. However, excess free iron could participate in the formation of reactive oxygen species via the Fenton reaction and is thought to be the primary mechanism for the pathogenesis of diseases ...
Omar, Syaliza Binti
core  

Baicalin, a Flavone, Induces the Differentiation of Cultured Osteoblasts

, 2011
Flavonoids, a group of natural compounds found in a variety of vegetables and herbal medicines, have been intensively reported on regarding their estrogen-like activities and particularly their ability to affect bone metabolism.
Karl W.K. Tsim, Chen, Ji J., Ji J. Chen, Roy C.Y. Choi, Tsim, Karl W.K., Anna W.H. Cheung, Sherry L. Xu, Choi, Roy C.Y., Chen, Vicky P., Cheung, Anna W.H., Dong, Tina T.X., Xu, Sherry L., Guo, Ava J.Y., Vicky P. Chen, Tina T.X. Dong, Ava J.Y. Guo   +15 more
core   +1 more source