Results 101 to 110 of about 10,947 (224)

Baicalin prevents Candida albicans infections via increasing its apoptosis rate

, 2014
BackgroundThese experiments were employed to explore the mechanisms underlying baicalin action on Candida albicans.Methodology and principal findingsWe detected the baicalin inhibition effects on three isotope-labeled precursors of 3H-UdR, 3H-TdR and 3H ...
Yang, Shulong, Xu, Jing, Fu, Yingyuan, Wu, Xiuzhen, Zeng, Xiaoping, Kuang, Nanzhen, Zhou, Zhixing, Zeng, Yurong   +7 more
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Baicalin Inhibits NOD-Like Receptor Family, Pyrin Containing Domain 3 Inflammasome Activation in Murine Macrophages by Augmenting Protein Kinase A Signaling

Frontiers in Immunology, 2017
The flavonoid baicalin has been reported to possess potent anti-inflammatory activities by suppressing inflammatory signaling pathways. However, whether baicalin can suppress the activation of NOD-like receptor (NLR) family, pyrin containing domain 3 ...
Chen-Guang Li, Liang Yan, Feng-Yi Mai, Zi-Jian Shi, Li-Hui Xu, Yan-Yun Jing, Qing-Bing Zha, Dong-Yun Ouyang, Xian-Hui He   +8 more
doaj   +1 more source

Survival rate of septic mice after injection with baicalin.

, 2012
Baicalin improves survival of polymicrobial sepsis in CLP mice. In the bai group, mice were treated with intra-peritoneal baicalin (100 mg/kg) at 1 h, 6 h and 12 h after CLP. Normal saline of equal volume was administered in sham and CLP groups.
Jiali Zhu (165939), Youping Wu (165958), Jiafeng Wang (165941), Ying Sheng (34711), Jinbao Li (165963), Lulong Bo (165947), Feng Chen (25347), Yun Zou (165943), Jingsheng Lou (165949), Xiaohua Fan (165952), Xiaoming Deng (165962), Rui Bao (165955), Fei Wang (19534)   +12 more
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Data of “Baicalin inhibits Salmonella typhimurium-induced inflammation and autophagy through the TLR4/MAPK pathway”

, 2020
Results1. Effects of Baicalin on cell viability and LDH productionNote:RAW264.7 cells viability——RAW细菌感染细胞活性H9 cells viability——H9细菌感染细胞活性1——control group；2——S. typhimurium group；3,4,5——S.
Ling, Z (via Mendeley Data)
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Baicalin attenuates PD-1/PD-L1 axis-induced immunosuppression in piglets challenged with Glaesserella parasuis by inhibiting the PI3K/Akt/mTOR and RAS/MEK/ERK signalling pathways

Veterinary Research
Infection of piglets with Glaesserella parasuis (G. parasuis) induces host immunosuppression. However, the mechanism underlying the immunosuppression of piglets remains unclear.
Shulin Fu, Jingyang Li, Jiarui You, Siyu Liu, Qiaoli Dong, Yunjian Fu, Ronghui Luo, Yamin Sun, Xinyue Tian, Wei Liu, Jingyi Zhang, Yu Ding, Yitian Zhang, Wutao Wang, Ling Guo, Yinsheng Qiu   +15 more
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Metabolism of glycyrrhizin and baicalin by human intestinal bacteria

, 1996
By human intestinal bacteria, glycyrrhizin (18β-glycyrrhetic acid β-D-glucuronyl α-D-glucuronic acid, GL) and baicalin (baicalein β-D-glucuronic acid) were metabolized to glycyrrhetinic acid and baicalin, respectively.
Kyeu-Yup Lee, Il-Sung Jang, Dong-Hyun Kim, Eun-Ah Jung, Hyeong Kyu Lee   +4 more
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Baicalin Ameliorates Imiquimod-Induced Psoriasis-Like Inflammation in Mice

, 2018
Baicalin is the main flavonoid from the roots of an important medicinal plant, Scutellaria baicalensis, which shows a variety biological activities. Psoriasis is a chronic immune-mediated inflammatory disease that affects the skin.
Jia Jiang, Jiunn-Wang Liao, Chien-Neng Wang, Chien-Hui Hung, Ya-Wen Chao, Huei-Hsuan Cheng, Chen-Chen Lee, Yi-Ting Chen   +7 more
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Baicalin reduces inflammation to inhibit lung cancer via targeting SOCS1/NF-κB/STAT3 axis

Heliyon
Inflammation affects several aspects of lung cancer progression including cell proliferation, metastasis, apoptosis, angiogenesis, and drug resistance.
Lijuan Guo, Ming Yue, Chengyuan Ma, Yunjing Wang, Jiejie Hou, Hong Li   +5 more
doaj   +1 more source

Antihyperglycemic Effects of Baicalin on Streptozotocin – Nicotinamide induced Diabetic Rats

, 2011
The aim of the study was to investigate the effects of baicalin on blood glucose, insulin and cytokine levels. Rat diabetes was induced by intraperitoneal (i.p.) injection of nicotinamide and streptozotocin. Diabetic rats were dosed with i.p. baicalin or
Wu, XD, Li, Huan-Ting, Davey, A.K., Wang, J., K. Davey, Andrew, Xiao-Dong Wu, Li, H.T., Jiping Wang, Li, HT, Wang, J, Wu, X.D., Wang, Jiping, Andrew K. Davey, Wu, Xiao-Dong, Huan-Ting Li, Davey, AK   +15 more
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Baicalin alleviates lead-induced cognitive dysfunction by modulating apoptosis and autophagy in mice

Ecotoxicology and Environmental Safety
Lead exposure is a well-documented environmental neurotoxin that poses a persistent threat to brain development. Excessive lead accumulation in this region impairs cognitive function and induces neuronal damage, yet effective therapeutic interventions ...
Jia Yu, Dahai Yu, Yong Pang, Weiyun Zhang, Shuang Liu, Xuexun Fang, Jie Zhang   +6 more
doaj   +1 more source