Results 81 to 90 of about 9,549 (183)

Baicalin reduces inflammation to inhibit lung cancer via targeting SOCS1/NF-κB/STAT3 axis

Heliyon
Inflammation affects several aspects of lung cancer progression including cell proliferation, metastasis, apoptosis, angiogenesis, and drug resistance.
Lijuan Guo, Ming Yue, Chengyuan Ma, Yunjing Wang, Jiejie Hou, Hong Li   +5 more
doaj   +1 more source

Baicalin alleviates lead-induced cognitive dysfunction by modulating apoptosis and autophagy in mice

Ecotoxicology and Environmental Safety
Lead exposure is a well-documented environmental neurotoxin that poses a persistent threat to brain development. Excessive lead accumulation in this region impairs cognitive function and induces neuronal damage, yet effective therapeutic interventions ...
Jia Yu, Dahai Yu, Yong Pang, Weiyun Zhang, Shuang Liu, Xuexun Fang, Jie Zhang   +6 more
doaj   +1 more source

Transcriptome Sequencing Explores the Mechanism of Baicalin on Bone Cancer Pain

Journal of Inflammation Research, 2021
Aitao Wang,1 Dongmei Guo,1 Hongyu Cheng,2 Hui Jiang,3 Xiaojuan Liu,1 Zhizhong Yun4 1Department of Anesthesiology, Inner Mongolia People’s Hospital, Hohhot, Inner Mongolia, 010017, People’s Republic of China; 2Department of Anesthesiology, Inner Mongolia ...
Wang A, Guo D, Cheng H, Jiang H, Liu X, Yun Z   +5 more
doaj  

Preparation, characterisation and in vitro anti-inflammatory activity of Baicalin microsponges

Heliyon
Baicalin, a flavonoid extracted from traditional Chinese medicine, Scutellaria baicalensis has significant anti-inflammatory effects. Microsponges are drug delivery systems that improve drug stability and slow the release rate.
Miao Li, Jiajie Gan, Xuhui Xu, Shuai Zhang, Yuanyuan Li, Le Bian, Zibo Dong   +6 more
doaj   +1 more source

Baicalin induces apoptosis and autophagy in resistant human hepatocellular carcinoma cell line Bel-7402/5-FU cells via PI3K/AKT pathway

Journal of Holistic Integrative Pharmacy
Objective: Multidrug resistance (MDR) is one main cause of chemotherapy failure. Baicalin is an important active ingredient with anticancer potential in many Chinese herbal medicines.
Fei Li, Zilin Lan, Weiwei Jiang, Jianheng Zhou, Jiumao Lin, Jinyan Zhao   +5 more
doaj   +1 more source

The protective role of baicalin regulation of autophagy in cancers

Cytotechnology
Autophagy is a conservative process of self degradation, in which abnormal organelles, proteins and other macromolecules are encapsulated and transferred to lysosomes for subsequent degradation. It maintains the intracellular balance, and responds to cellular conditions such as hunger or stress.
Zhang, Qi, Guo, Shiyun, Ge, Hangwei, Wang, Honggang   +3 more
openaire   +2 more sources

Phosphatase PTP-4 downregulates ATLN-1-mediated host defense against <i>Pseudomonas aeruginosa</i> infection in <i>Caenorhabditis elegans</i>. [PDF]

Front Pharmacol
Xie J, Shi G, Wang M, Zhong Y, Yuan Y, Sun L, Ge B, Xu A.   +7 more
europepmc   +1 more source

Baicalin improves the inflammatory response of RA-FLS by targeting the circ_0000734/miR-197-5p/IKBKB axis. [PDF]

Front Immunol
Sun Y, Liu J, He M, Chen X.
europepmc   +1 more source

Baicalin suppresses colorectal cancer proliferation and induces M1 polarization of tumor-associated macrophages by promoting proteasomal degradation of HK2. [PDF]

Front Immunol
Bai DH, Gao D, Xiong Y, Chang YL, Gan X, Yang L, Wang PP, Zhang RH.   +7 more
europepmc   +1 more source

The Antibacterial Mechanism of Baicalin and Its Solubilization Strategy. [PDF]

Molecules
Ning C, Yang Y, Yu Z, Sun Y, Meng X, Dong Z, Guo H.   +6 more
europepmc   +1 more source