Results 81 to 90 of about 11,830 (227)

The effects of baicalin on piglets challenged with Glaesserella parasuis

open access: yesVeterinary Research, 2020
Glaesserella parasuis (G. parasuis) causes porcine vascular inflammation and damage. Baicalin is reported to have antioxidant and anti-inflammatory functions. However, whether baicalin protects piglets against G.
Shulin Fu   +11 more
doaj   +1 more source

Investigating Overweight and Obesity Risk in Shift Workers Using Omics Technologies

open access: yesObesity Reviews, EarlyView.
ABSTRACT Night shift workers are at higher risk of developing overweight and obesity. The disruption of the physiological circadian rhythm leads to metabolic alterations, such as decreased insulin sensitivity, increased adipogenesis, and inflammation, with effects on their health and leading, among other diseases, to obesity.
Katrin Scionti   +3 more
wiley   +1 more source

Baicalin Weakens Staphylococcus aureus Pathogenicity by Targeting Sortase B [PDF]

open access: yes, 2018
Staphylococcus aureus (S. aureus) is a human and other animal pathogen that contributes to the primary etiology of nosocomial pneumonia, a disease with high mortality rates and costs. Treatment of multidrug-resistant S.
Yawen Gao   +4 more
core   +1 more source

Baicalin Alleviates Lipopolysaccharide-Induced Liver Inflammation in Chicken by Suppressing TLR4-Mediated NF-κB Pathway

open access: yesFrontiers in Pharmacology, 2017
As a kind of potent stimulus, lipopolysaccharide (LPS) has the ability to cause cell damage by activating toll-like receptor(TLR)4, then nuclear factor kappa B (NF-κB) translocates into the nucleus and changes the expression of related inflammatory genes.
Ping Cheng   +9 more
doaj   +1 more source

Baicalin Alleviates Lactational Heat‐Stress‐Induced Hepatic Mitochondrial Dysfunction via Sirt3‐Dependent Deacetylation of NDUFS1

open access: yesFood Frontiers, Volume 7, Issue 6, November 2026.
This study reveals that lactational HS suppresses Sirt3 activity, leading to hyperacetylation of the complex I subunit NDUFS1, and excessive mitochondrial ROS production, whereas BAI, a nature food‐derived bioactive compound, alleviates lactational HS‐induced hepatic mitochondrial injury by activating the Sirt3–NDUFS1 axis to deacetylate mitochondrial ...
Jingzheng Li   +3 more
wiley   +1 more source

Biocatalytic Synthesis of Lipophilic Baicalin Derivatives as Antimicrobial Agents

open access: yes, 2019
Enzymatic acylation is commonly used to increase the lipophilicity of flavonoids. However, the absence of primary hydroxyl groups makes it challenging to acylate baicalin using traditional acylation methods.
Mengmeng Zhang (1507543)   +3 more
core   +1 more source

Design Considerations for Polymer–Deep Eutectic Solvent Hybrid Systems for Transdermal Drug Delivery

open access: yesJournal of Applied Polymer Science, Volume 143, Issue 40, October 20, 2026.
Deep eutectic solvents (DESs) act as tunable, green excipients that modulate polymer structure–property relationships to enhance drug solubility, skin permeation, stability, and controlled release. Through hydrogen‐bond interactions, DES–polymer hybrid systems enable improved transdermal performance, offering a rational, design‐driven platform for ...
Madhavi Kailas Kapale   +3 more
wiley   +1 more source

The Therapeutic Effects of Baicalin on Vitiligo Mice

open access: yesBiological and Pharmaceutical Bulletin, 2019
Vitiligo is a commom disease of skin. Its pathogenesis is complex, resulting in the incapacity to find a targeted cure. Baicalin, which is isolated from Scutellariae radix, has been known to exhibit a number of pharmacological effects on autoimmune diseases.
Zhu, Yiping   +4 more
openaire   +3 more sources

Polyphenols as Natural Therapeutics for Dental Infections and Oral Inflammation: Mechanisms and Clinical Perspectives

open access: yesChemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Polyphenol‐rich plant extracts provide natural immunomodulatory protection for oral health through complementary antioxidant, antibacterial, and anti‐inflammatory actions. Their potential to reduce harmful microbial activity and inflammation highlights the promise of dietary polyphenols as a natural strategy for maintaining oral health and preventing ...
Deepa Subramanian   +3 more
wiley   +1 more source

Baicalin protects against hepatocyte injury caused by aflatoxin B1 via the TP53-related ferroptosis Pathway

open access: yesEcotoxicology and Environmental Safety
Objective: Baicalin has antioxidative, antiviral, and anti-inflammatory properties. However, its ability to alleviate oxidative stress (OS) and DNA damage in liver cells exposed to aflatoxin B1 (AFB1), a highly hepatotoxic compound, remains uncertain. In
Han-Jing Zhang   +10 more
doaj   +1 more source

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