Results 61 to 70 of about 10,947 (224)

Baicalin Attenuates Cardiac Dysfunction and Myocardial Remodeling in a Chronic Pressure-Overload Mice Model

Cellular Physiology and Biochemistry, 2017
Background/Aims: Baicalin has been shown to be effective for various animal models of cardiovascular diseases, such as pulmonary hypertension, atherosclerosis and myocardial ischaemic injury.
Yanqing Zhang, Pingping Liao, Meng’en Zhu, Wei Li, Dan Hu, Siming Guan, Long Chen   +6 more
doaj   +1 more source

Traditional Chinese Medicine for lung cancer: Mechanisms, clinical evidence, and future perspectives

Precision Medical Sciences, EarlyView.
Graphical abstract represents the risk factors for lung cancer, TCM efficacy and clinical outcomes to future challenges. Abstract Lung cancer remains a leading cause of global cancer mortality. Despite advances in conventional treatments such as surgery, chemotherapy, targeted therapy, and immunotherapy, challenges including drug resistance, toxicity ...
Zhangdeng Chen, Liujun Bao
wiley   +1 more source

Structure of baicalin and baicalein.

, 2018
Structure of baicalin and baicalein.
Youlin Zhu (4849585), Xin Yan (17064), Limin Fang (4849576), Shurui Song (4849582), Hu Su (4849579), Bin Zeng (3474053)   +5 more
core   +1 more source

The protective effect of baicalin against cyclophosphamideinduced testicular damage in rats

Open Veterinary Journal
Background: Cyclophosphamide (CTX) is a widely used chemotherapeutic agent; however, its clinical application is often limited by significant reproductive toxicity, particularly testicular damage.
Jianqin Li, Chunlian Song, Xue Zhang, Yalong Sun, Nan Wang, Xianghua Shu   +5 more
doaj   +1 more source

Inspiration for COVID-19 Treatment: Network Analysis and Experimental Validation of Baicalin for Cytokine Storm

Frontiers in Pharmacology, 2022
Background: Cytokine storm (CS) is a systemic inflammatory syndrome and a major cause of multi-organ failure and even death in COVID-19 patients. With the increasing number of COVID-19 patients, there is an urgent need to develop effective therapeutic ...
Jia You, Huawei Li, Peng Fan, Xi Yang, Yuanfeng Wei, Lingnan Zheng, Zhaojun Li, Cheng Yi   +7 more
doaj   +1 more source

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

Phytotherapy Research, EarlyView.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee, Yu Jin So, Il‐Joo Jo, Ji Yong Jang, Tae Han Yook, Jun Ho Lee, Sung Wook Kim, Kangwook Lee, Soo Jung Park, Gabsik Yang   +9 more
wiley   +1 more source

Table_1_SbWRKY75- and SbWRKY41-mediated jasmonic acid signaling regulates baicalin biosynthesis.docx

, 2023
IntroductionScutellaria baicalensis Georgi is a traditional Chinese medicinal plant with broad pharmacological activities whose main active ingredient is the flavonoid baicalin.
Shi Qiu (425335), Shi Qiu, Zongyou Lv (378800), Wansheng Chen (190172), Kaixian Chen, Kaixian Chen (19449), Shiyuan Fang, Ying Xiao (6517), Chen Zhang (66790), Chen Zhang, Zongyou Lv, Ying Xiao, Shiyuan Fang (7280018), Wansheng Chen   +13 more
core   +1 more source

Consecutive baicalin treatment relieves its accumulation in rats with intrahepatic cholestasis by increasing MRP2 expression

Heliyon, 2023
Baicalin, an important flavonoid isolated from Scutellaria baicalensis Georgi, is a Chinese herb widely used in clinical practice. We previously reported the in vivo accumulation of baicalin in rats with intrahepatic cholestasis (IHC) after a single dose.
Yue Zu, Yanan Liu, Lulu Lan, Chen Zhu, Chengliang Zhang, Dong Liu   +5 more
doaj   +1 more source

Flavonoids in Nasal Therapeutics: Biological Activities, Delivery Challenges, and Formulation Strategies–A Systematic Review

Phytotherapy Research, EarlyView.
Overview of the therapeutic potential of flavonoids in nasal delivery systems, highlighting their benefits to the human nasal cavity, and applications in the treatment of respiratory and brain‐related diseases. ABSTRACT Flavonoids represent a significant group of secondary metabolites.
Jeniffer Viviana Ramirez Hernández, Sara Elis Bianchi, Flávia Nathiely Silveira Fachel, Elizandra Braganhol, Sheila Porto de Matos, Valquíria Linck Bassani   +5 more
wiley   +1 more source

The molecular structure of baicalin.

, 2013
The molecular structure of baicalin.
Zhengyuan Zhang (491725), Ti Zhang (134349), Guangrong Zhou (491723), Xiaoming Yuan (438660), Aiwen Feng (491722), Xinli Huang (491724)   +5 more
core   +1 more source