Results 61 to 70 of about 9,549 (183)

Gut Microbiota and Ischemic Stroke: From Pre‐Stroke Dysbiosis and Acute‐Phase Changes to Therapeutic Applications

Brain and Behavior, Volume 16, Issue 8, August 2026.
Abstract Purpose Ischemic stroke poses a major global health burden, and growing evidence points to the microbiota–gut–brain axis as an important contributor to stroke pathophysiology and recovery. The purpose of this review is to summarize current knowledge on bidirectional gut‐brain communication in stroke, establishing gut dysbiosis as an upstream ...
Ruihui Weng, Gaolei Dong, Jianxin Tang, Yu Zhao   +3 more
wiley   +1 more source

Pharmacological actions of baicalin and baicalein

Folia Pharmacologica Japonica, 1970
In the Chinese medicine, Scutellaria baicalensis GEORG has been used as a remedy for some of allergic diseases. Therefore, the authors investigated the effects of baicalin and baicalein, components of the drug, on active anaphylactic reaction in guinea pig, and the results obtained were compared with those of rutin, methylhesperidin and quercetin.
KODA, Akihide, NAGAI, Hiroichi, WADA, Hiroshi   +2 more
  +6 more sources

Study of the antitumor activity of the combination baicalin and epigallocatechin gallate in a murine model of vincristine-resistant breast cancer [PDF]

Pharmacia
Background: Breast cancer is one of the primary causes of death in women worldwide. Yearly, a quarter of cancer cases in women are breast cancer. The problem is aggravated by the emergence of chemotherapeutic resistance.
Dima Awajan, Anas H. A. Abu-Humaidan, Wamidh H. Talib   +2 more
doaj   +3 more sources

Network Pharmacology Combined With Metabonomics and Transcriptomics Reveals the Mechanism of Rubus Chingii Hu in Alleviating Nephrotoxicity Caused by Tripterygium Glycosides Tablet

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
Flow chart of RCH to improve TGT‐induced nephrotoxicity. ABSTRACT Researches on Tripterygium glycosides tablets (TGT) often overlook renal toxicity from prolonged use. Rubus chingii Hu (RCH) is beneficial to kidney health and has an unclear role in reducing nephrotoxicity.
Cong Zhang, Zepeng Zhang, Tong Zhou, Lei Zhang   +3 more
wiley   +1 more source

Effect of baicalin and baicalin-bovine serum albumin nanoparticle against bendiocarb exposure in rats

Toxicology Research
Abstract Background The aim of the study was to investigate the effect of baicalin and baicalin-bovine serum albumin nanoparticles against bendiocarb exposure in rats. Methods Eighty male Wistar Albino rats aged 4–6 weeks were used ...
Coşkun Aslan, Gökhan Eraslan
openaire   +4 more sources

Targeted Interventions in HAM/TSP: Emerging Therapies and Future Directions – A Narrative Review

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aim Human T‐Lymphotropic virus type 1 (HTLV‐1) infection can lead to HTLV‐1‐associated myelopathy/tropical spastic paraparesis (HAM/TSP), a debilitating chronic neurological disease characterized by progressive lower limb spasticity and autonomic dysfunction.
Meygol Mirzaei Rezaei, Mahdi Khosravi Nia, Kasra Allaei Rouzbahani, Maryam Kazemi, Negar Asghari Hosori, Mehdi Norouzi, Farzaneh Sotoudegan, Narges Eslami, Negar Ariamand, Vahid Shahnavaz, Arash Letafati, Sayed‑Hamidreza Mozhgani   +11 more
wiley   +1 more source

Baicalin Protects Mouse Testis From Injury Induced by PM2.5 Associated With the DKK1‐Wnt/β‐Catenin Signaling Pathway

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
ABSTRACT Fine particulate matter (PM2.5) has a damaging effect on the male reproductive system. Baicalin has excellent anti‐inflammatory and antioxidant pharmacological functions. The main purpose of this study was to investigate whether baicalin had a protective effect against PM2.5‐induced damage to the reproductive system of mice, and to further ...
Lili Deng, Juan Wang, Shuyin Li, Yaping Mao, Ye Sun, Qiaoqiao Yang, Zhenghui Xie, Chen Zhang, Shuo Gong, Chunling Xiao, Mingyue Ma   +10 more
wiley   +1 more source

Phenolic composition and multi‐target bioactivities of Globularia alypum extracts across seasons

JSFA reports, Volume 6, Issue 8, Page 314-330, August 2026.
Abstract Background This study investigates the influence of seasonal variation on the phytochemical profile and biofunctional activities of ethanolic leaf extracts from Globularia alypum. Leaves collected across four seasons were extracted with a hydroethanolic solvent (80:20, v/v) and analyzed by LC‐ESI‐MS/MS.
Mohammed Messaoudi, Khalil Guelift, Mokhtar Benmohamed, Khaled Kherraz, Latifa Khattabi, Afaf Khadra Bendrihem, Khaled Aggoun, Barbara Sawicka, Lilya Harchaoui, Mohamed Amine Ferhat, Salah Neghmouche Nacer, Stefania Garzoli   +11 more
wiley   +1 more source

Baicalin Protects Mice Brain From Apoptosis in Traumatic Brain Injury Model Through Activation of Autophagy

Frontiers in Neuroscience, 2019
Autophagy is associated with secondary injury following traumatic brain injury (TBI) and is expected to be a therapeutic target. Baicalin, a neuroprotective agent, has been proven to exert multi-functional bioactive effects in brain injury diseases ...
Jiang Fang, Jiang Fang, Yihao Zhu, Yihao Zhu, Handong Wang, Handong Wang, Bailu Cao, Bailu Cao, Maoxing Fei, Maoxing Fei, Wenhao Niu, Wenhao Niu, Yuan Zhou, Yuan Zhou, Xiaoliang Wang, Xiaoliang Wang, Xiang Li, Mengliang Zhou, Mengliang Zhou   +18 more
doaj   +1 more source

The Role of Inflammation and Immunity in Cardiovascular Disease: Molecular Mechanisms and Therapeutic Targets

MedComm, Volume 7, Issue 8, August 2026.
Inflammation in cardiovascular disease is a dynamic and context‐dependent network rather than a secondary response to injury. Mitochondrial danger signaling links metabolic stress to immune activation through TLR priming, NLRP3 inflammasome amplification, cGAS–STING signaling, and immunometabolic gating, providing a basis for more precise therapeutic ...
Jiaxiang Rong, Zhen Wang, Xiaoxiao Lin, Ziwen Lei, Qianqian Huang, Hang Liu, Fei Luan, Junbo Zou, Yajun Shi   +8 more
wiley   +1 more source