Results 51 to 60 of about 10,947 (224)

Beyond Gut Modulation: A Critical Review of the Therapeutic Potential, Safety, and Clinical Prospects of Natural Polysaccharides for IBD

open access: yesFood Safety and Health, EarlyView.
In this review, we critically summarized the application of natural polysaccharides (NPs) for the treatment of IBD. This approach combines, in a unique way (right), the basic structure–activity relationships of NPs from different origins (left) with their multipronged mode of action, which involves modulation of the gut microbiota and other ...
Felix Danso   +3 more
wiley   +1 more source

Effect of baicalin treatment on CZN pharmacokinetics.

open access: yes, 2013
(A) (B)The concentration-time profile of CZN (15 mg/kg,iv) after treatment with saline (control) or baicalin in rats. (C) (D) The changes in CZN (15 mg/kg, i.v) concentrations (%) after treatment with baicalin compared with control.
Na Gao (137976)   +2 more
core   +1 more source

Traditional Chinese Medicine and Natural Products Targeting Right Ventricular Dysfunction in Pulmonary Arterial Hypertension: Toward Precision Cardiometabolic Therapy

open access: yesiNew Medicine, EarlyView.
Natural products and traditional Chinese medicine target metabolic pathways underlying right ventricular dysfunction in pulmonary arterial hypertension. Integrating multi‐omics, artificial intelligence, and systems biology may enable precision cardiometabolic therapies to restore right ventricular metabolism and improve clinical outcomes.
Yihao Wu, Zhehui Tang, Hongwei Yao
wiley   +1 more source

Development of Eastern Blotting Technique for Analysis of Baicalin Using Anti-Baicalin Monoclonal Antibody [PDF]

open access: yesAntibodies, 2012
Scutellariae radix (S. radix) is one of the most important crude drugs used in Kampo medicines (KMs). A part of its pharmaceutical properties is due to flavone glycoside, baicalin (BI). A technique named eastern blotting was developed for the specific and easy identification of BI in the extracts of crude drugs and KMs using anti-BI monoclonal antibody
Osamu Morinaga   +6 more
openaire   +2 more sources

Baicalin Improves Antioxidant Status of Streptozotocin-Induced Diabetic Wistar Rats

open access: yes, 2016
This study investigated the antioxidant and antidiabetic effects of baicalin, as well as its effects in combination with the antidiabetic drug metformin. Three groups of streptozotocin-induced diabetic rats were given the following treatments for 30 days:
Annie Hsu (330347)   +3 more
core   +1 more source

The Anti-Diabetic Potential of Baicalin: Evidence from Rodent Studies

open access: yes, 2023
Baicalin is a biologically active flavonoid compound that benefits the organism in various pathological conditions. Rodent studies have shown that this compound effectively alleviates diabetes-related disturbances in models of type 1 and type 2 diabetes.
Tomasz Szkudelski, Katarzyna Szkudelska
core   +1 more source

Inhibition of baicalin on metabolism of phenacetin, a probe of CYP1A2, in human liver microsomes and in rats.

open access: yesPLoS ONE, 2014
Baicalin has been used as mainly bioactive constituent of about 100 kinds of traditional Chinese medicines in Chinese pharmacopoeia. The effect of baicalin on cytochrome P450 should be paid more attention because baicalin was used widely. The aim of this
Na Gao   +6 more
doaj   +1 more source

Phenolic composition and multi‐target bioactivities of Globularia alypum extracts across seasons

open access: yesJSFA reports, EarlyView.
Abstract Background This study investigates the influence of seasonal variation on the phytochemical profile and biofunctional activities of ethanolic leaf extracts from Globularia alypum. Leaves collected across four seasons were extracted with a hydroethanolic solvent (80:20, v/v) and analyzed by LC‐ESI‐MS/MS.
Mohammed Messaoudi   +11 more
wiley   +1 more source

Chemical Structure of baicalin (BC).

open access: yes, 2014
Chemical Structure of baicalin (BC).
Xiumin Li (401087)   +14 more
core   +1 more source

Baicalin Weakens Staphylococcus aureus Pathogenicity by Targeting Sortase B [PDF]

open access: yes, 2018
Staphylococcus aureus (S. aureus) is a human and other animal pathogen that contributes to the primary etiology of nosocomial pneumonia, a disease with high mortality rates and costs. Treatment of multidrug-resistant S.
Yawen Gao   +4 more
core   +1 more source

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