Results 51 to 60 of about 11,830 (227)

The Anti-Diabetic Potential of Baicalin: Evidence from Rodent Studies

open access: yes, 2023
Baicalin is a biologically active flavonoid compound that benefits the organism in various pathological conditions. Rodent studies have shown that this compound effectively alleviates diabetes-related disturbances in models of type 1 and type 2 diabetes.
Tomasz Szkudelski, Katarzyna Szkudelska
core   +1 more source

Baicalin Mitigates Cardiac Hypertrophy and Fibrosis by Inhibiting the p85a Subunit of PI3K

open access: yesBiomedicines
Background: Heart failure (HF) is a serious public health concern. Baicalin is one of the major active ingredients of a traditional Chinese herbal medicine, Huang Qin, which is used to treat patients with chest pain or cardiac discomfort.
Lu He   +5 more
doaj   +1 more source

Development of Eastern Blotting Technique for Analysis of Baicalin Using Anti-Baicalin Monoclonal Antibody [PDF]

open access: yesAntibodies, 2012
Scutellariae radix (S. radix) is one of the most important crude drugs used in Kampo medicines (KMs). A part of its pharmaceutical properties is due to flavone glycoside, baicalin (BI). A technique named eastern blotting was developed for the specific and easy identification of BI in the extracts of crude drugs and KMs using anti-BI monoclonal antibody
Morinaga, Osamu   +6 more
openaire   +2 more sources

Beyond Gut Modulation: A Critical Review of the Therapeutic Potential, Safety, and Clinical Prospects of Natural Polysaccharides for IBD

open access: yesFood Safety and Health, EarlyView.
In this review, we critically summarized the application of natural polysaccharides (NPs) for the treatment of IBD. This approach combines, in a unique way (right), the basic structure–activity relationships of NPs from different origins (left) with their multipronged mode of action, which involves modulation of the gut microbiota and other ...
Felix Danso   +3 more
wiley   +1 more source

Inhibition of baicalin on metabolism of phenacetin, a probe of CYP1A2, in human liver microsomes and in rats.

open access: yesPLoS ONE, 2014
Baicalin has been used as mainly bioactive constituent of about 100 kinds of traditional Chinese medicines in Chinese pharmacopoeia. The effect of baicalin on cytochrome P450 should be paid more attention because baicalin was used widely. The aim of this
Na Gao   +6 more
doaj   +1 more source

Traditional Chinese Medicine and Natural Products Targeting Right Ventricular Dysfunction in Pulmonary Arterial Hypertension: Toward Precision Cardiometabolic Therapy

open access: yesiNew Medicine, EarlyView.
Natural products and traditional Chinese medicine target metabolic pathways underlying right ventricular dysfunction in pulmonary arterial hypertension. Integrating multi‐omics, artificial intelligence, and systems biology may enable precision cardiometabolic therapies to restore right ventricular metabolism and improve clinical outcomes.
Yihao Wu, Zhehui Tang, Hongwei Yao
wiley   +1 more source

The structures of baicalin, jasminoidin and cholic acid. A. baicalin; B. jasminoidin; C. cholic acid.

open access: yes, 2013
The structures of baicalin, jasminoidin and cholic acid. A. baicalin; B. jasminoidin; C. cholic acid.
Zhanjun Zhang (379921)   +6 more
core   +1 more source

Dissolution and pharmacokinetics of baicalin–polyvinylpyrrolidone coprecipitate

open access: yesJournal of Pharmacy and Pharmacology, 2013
Abstract Objectives Baicalin–polyvinylpyrrolidone coprecipitate was prepared with the aim of improving the dissolution and bioavailability of the baicalin. Methods The dissolution of the coprecipitate in capsule form was tested and ...
Bibo, Li   +10 more
openaire   +2 more sources

From nature to nanoscale: advances, challenges, and preclinical translation of nanofiber drug delivery systems containing plant‐derived active ingredients

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract Since the early 1960s, nanotechnology has been a critical area of science, allowing for the development of sophisticated nanomaterials. Nanofibers, one of the most widely used nanotechnological drug delivery systems, have emerged as a highly versatile platform within modern pharmaceutical sciences.
Heybet Kerem Polat   +7 more
wiley   +1 more source

Effect of baicalin treatment on CZN pharmacokinetics.

open access: yes, 2013
(A) (B)The concentration-time profile of CZN (15 mg/kg,iv) after treatment with saline (control) or baicalin in rats. (C) (D) The changes in CZN (15 mg/kg, i.v) concentrations (%) after treatment with baicalin compared with control.
Na Gao (137976)   +2 more
core   +1 more source

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