Results 231 to 240 of about 20,980 (270)

The Antibacterial Activities and Effects of Baicalin on Ampicillin Resistance of MRSA and Stenotrophomonas maltophilia

Foodborne pathogens and disease
The development of novel antibacterial agents from plant sources is emerging as a successful strategy to combat antibiotic resistance in pathogens.
Kun Chen, Xiaojing Liu, Lin Song, Ying Wang, Jingwen Zhang, Yaxin Song, Haonan Zhuang, Jinling Shen, Jielin Yang, Chuantao Peng, Jinhong Zang, Qingli Yang, Day Li, Tanushree B. Gupta, Dehua Guo, Zhaojie Li   +15 more
semanticscholar   +1 more source

Baicalin induces Mrgprb2-dependent pseudo-allergy in mice

Immunology Letters, 2020
Baicalin, a component of traditional Chinese medicine, is one of the main compounds present in Scutellaria baicalensis Georgi. Pseudo-allergy induced by the injection of these medicines is a frequent adverse drug reaction. Therefore, elucidation of the anaphylactoid reaction of baicalin and its underlying mechanisms are important.
Jue, Wang, Yongjing, Zhang, Delu, Che, Yingnan, Zeng, Yuanyuan, Wu, Qiaohong, Qin, Nan, Wang   +6 more
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Response of Human Periodontal Ligament Cells to Baicalin

Journal of Periodontology, 2014
Background: Periodontitis is the most common cause of tooth loss in adults. Periodontal ligament cell (PLC)–based therapy is considered one of the most promising methods in periodontal tissue regeneration. The traditional Chinese medicine baicalin has been shown to possess antimicrobial and anti‐inflammatory activities and enhance cell proliferation ...
Zhenhua, Pei, Baokui, Wang, Fengqiu, Zhang, Zhongying, Niu, Shenggen, Shi, Richard D, Cannon, Li, Mei   +6 more
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[A histochemical study on baicalin].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2001
Baicalin in the root of Scutellaria baicalensis was analysed histochemically by means of TLC and HPLC. It was determined that the content of baicalin in phloem was 11.08%, in xylem 7.86%, in phellem 2.19% and in centric decayed part 0.815%. Thus the quality of root of Scutellaria baicalensis is believed to consist in thin phellem, high ratio of phloem ...
X, Du, B, Li, Y, Pan, , Mali
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Multiple ABC Transporters Efflux Baicalin.

Phytotherapy research : PTR, 2016
Baicalein, the aglycone formed by hydrolysis of baicalin in the intestine, is well absorbed by passive diffusion but subjected to extensive intestinal glucuronidation. Efflux of baicalin, the low passive permeability glucuronide of baicalein from enterocytes, likely depends on a carrier-mediated transport.
Bernadett, Kalapos-Kovács, Balázs, Magda, Márton, Jani, Zsolt, Fekete, Pál T, Szabó, István, Antal, Péter, Krajcsi, Imre, Klebovich   +7 more
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Baicalin is a substrate of OATP2B1 and OATP1B3

Phytotherapy Research, 2018
The use and significance of baicalin, the main bioactive component found in Radix Scutellaria, have been on the rise due to its interesting pharmacological properties. Baicalin, a low passive permeability compound, is directly absorbed from the upper intestine and its hepatic elimination is dominant.
Bernadett Kalapos‐Kovács, Viktória Juhász, Csilla Temesszentandrási‐Ambrus, Balázs Magda, Pál T. Szabó, István Antal, Imre Klebovich, Péter Krajcsi   +7 more
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Theoretical investigation of the conformational space of baicalin

Journal of Molecular Graphics and Modelling, 2017
Flavonoids are a large group of polyphenolic compounds ubiquitously present in plants. They are important components of human diet. They are recognized as potential drug candidates to be used in the treatment and prevention of a lot of pathological disorders, due to their protective effects.
Martínez Medina, Juan José, Ferrer, Evelina Gloria, Williams, Patricia Ana María, Okulik, Nora Beatriz   +3 more
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Preparation and characterization of baicalin-poly -vinylpyrrolidone coprecipitate

International Journal of Pharmaceutics, 2011
Baicalin-polyvinylpyrrolidone (PVP) coprecipitate was prepared by the solvent method of solid dispersion technology to improve the dissolution rate of baicalin. The coprecipitate was characterized using differential scanning calorimetry (DSC), X-ray powder diffraction (XRD), infrared spectrometry (IR) and dissolution testing.
Bibo, Li, Ming, Wen, Wei, Li, Mei, He, Xueheng, Yang, Shaolin, Li   +5 more
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Neuroprotective Mechanisms of Baicalin in Ischemia Stroke

ACS Chemical Neuroscience
Ischemic stroke (IS) remains one of the leading global causes of mortality and disability, imposing a substantial socioeconomic burden on families and healthcare systems. Despite recognition as a critical global health challenge, therapeutic interventions for cerebral ischemia remain severely limited.
Peng He, Ru Qiao, Can Liu, Weilong Zhang, Haiying Li, Fuyuan He   +5 more
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[Measurement of baicalin contents by HPLC].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2003
To compare the contents of baicalin in the raw medical material and the different prepared medical materials of Scutellaria baicalensis.The contents of baicalin were determined by HPLC. Chromatographic conditions included Hypersil C18 column and the mobile phase consisting of a mixture of methanol-0.04% phosphoric acid (46:54). Baicalin was detected at
Zhu-ying, He, Pei-xue, Cao, Guang-yi, Liang, Zai-chuan, Liu, Xing-guo, Wu   +4 more
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