Results 201 to 210 of about 952,428 (323)

Microglial reactivity and nodule formation are associated with Synaptodendritic damage in the brains of people with HIV‐1

Brain Pathology, EarlyView.
Despite effective ART, neurocognitive impairment persists in people with HIV. Brains from PWH present exacerbated microgliosis and formation of microglial nodules that are actively engaged in neuronal phagocytosis, resulting in neuronal injury and dendritic loss.
Roberta S. Dos Reis, Lauren A. Ignatz, Sathish Selvam, Marc C. E. Wagner, Sara Gianella, Antoine Chaillon, Vanessa Gomez‐Moreno, Jeremy Martison, Leah H. Rubin, Sabina Heberlen, Valentina Stosor, Jordan Lake, Velpandi Ayyavoo   +12 more
wiley   +1 more source

Comparison of Cultures and 16S/18S Amplicon-Based Microbiome Analyses for Diagnosing Nosocomial Pneumonia in Patients Admitted to the Intensive Care Unit-An Exploratory Study. [PDF]

Diagnostics (Basel)
Holmgaard DB, Nebrich L, Uslu B, Schouw CH, Dargis R, Pedersen HP, Fuursted K, Nielsen HV, Christensen JJ, Nielsen XC, Poulsen LM.   +10 more
europepmc   +1 more source

Are we hallucinating or can psychedelic drugs modulate the immune system to control inflammation?

British Journal of Pharmacology, EarlyView.
Psychedelic drugs that activate 5‐HT2A receptors have been long used for cultural, medicinal and recreational purposes. Interest in psychedelics for treating psychiatric disorders has resurged recently and is well documented; less well recognised are their anti‐inflammatory properties. Growing evidence now demonstrates that psychedelics modulate immune
Omar Qureshi, Jamie Cowley, Ashley Pegg, Alison J. Cooper, John Gordon, Catherine A. Brady, Antonio Belli, Sam Butterworth, Rachel Upthegrove, Nick Andrews, Nicholas M. Barnes   +10 more
wiley   +1 more source

Insulin-like growth factor-1/insulin-like growth factor-1 receptor signalling in macrophages facilitates recovery from acute lung injury. [PDF]

Ann Med
Niisato M, Yamashita M, Kawasaki Y, Furukawa H, Sato T, Kawada I.   +5 more
europepmc   +1 more source

Monocyte Chemotactic Factors in the Airways of Patients With Mild Asthma Before and After an Allergen Challenge

Allergy, EarlyView.
Nami Shrestha Palikhe, Yingqi Wu, Karen J. Howie, Caitlin Stevens, Jennifer Mitchell, Lesley Wiltshire, Gail M. Gauvreau, Harissios Vliagoftis   +7 more
wiley   +1 more source

PDE4D and PDE3B orchestrate distinct cAMP microdomains in 3T3‐L1 adipocytes

British Journal of Pharmacology, EarlyView.
Basal conditions: •Ins/PDE3B lowers cytoplasmic cAMP (cyt‐cAMP) without affecting plasma membrane cAMP (pm‐cAMP). •Insulin decreases lipid droplet cAMP (LD‐cAMP) independent of PDE3B. •FGF1/PDE4D modestly reduces both cyt‐ and pm‐cAMP, while PDE4D alone can modulate LD‐cAMP. ISO stimulation: •Ins/PDE3B has minimal impact on cyt‐cAMP.
Johannes Krier, David Spähn, David Arturo Juarez Lopez, Judith L. Nono, Judith Seigner, Lisa Jacob, Siegfried Ussar, Robert Lukowski, Andreas L. Birkenfeld, Gencer Sancar   +9 more
wiley   +1 more source

Comparison of Testicular Workup for Ischemia and Suspected Torsion (TWIST), Testicular Torsion (TT Lim), and Boettcher Alert (BAL) Scoring Systems for the Diagnosis of Testicular Torsion in 50 Surgical Cases. [PDF]

Cureus
Tobu S, Yamaguchi Y, Yukimoto M, Maeda A, Kusano S, Kakinoki Y, Kakinoki H, Kawasaki M, Noguchi M.   +8 more
europepmc   +1 more source

Seasonal Variation in PM_2.5 Composition Modulates Oxidative Stress and Neutrophilic Inflammation with Involvement of TLR4 Signaling. [PDF]

Antioxidants (Basel)
Wang D, Zeng Z, Nawata A, Baba R, Okazaki R, Okuda T, Yoshida Y.   +6 more
europepmc   +1 more source

Selective Targeting of IL‐1RAP‐Dependent Eosinophilic Inflammation in Allergic Fungal Airway Disease

Allergy, EarlyView.
Thomas J. Williams, James S. Griffiths, Luis E. Gonzales‐Huerta, David Bell, Anna K. Reed, Anand Shah, Julian R. Naglik, Darius Armstrong‐James   +7 more
wiley   +1 more source