Results 111 to 120 of about 9,265,447 (383)

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

In‐Stream Nitrogen Dynamics in a Point Source Influenced Headwater Stream During Baseflow Conditions

open access: yesWater Resources Research
Hydrochemical signatures are often traced back to their original sources using data collected at catchment outlets. However, this approach introduces uncertainties, as signals may add up, cancel each other out, or be subject to transformation processes ...
Caroline Spill   +2 more
doaj   +1 more source

Work and Family [PDF]

open access: yes, 1999
This survey offers in-depth analysis of workers' ability to balance work and family, the policies made available by employers to help their employees achieve this balance, and workers' attitudes about the policies designed to address the need to balance ...

core  

Balanced and functionally balanced P-groups

open access: yesTopological Algebra and its Applications, 2018
Abstract In relation to Itzkowitz’s problem [5], we show that a c-bounded P-group is balanced if and only if it is functionally balanced.We prove that for an arbitrary P-group, being functionally balanced is equivalent to being strongly functionally balanced.
openaire   +5 more sources

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

Sagittal balance of the spine

open access: yesEuropean spine journal, 2019
The static sagittal balance of the normal spine is a physiological alignment of the spine in the most efficient manner by the muscular forces. During gait, this balance is constantly thwarted by single-foot support.
J. Le Huec   +4 more
semanticscholar   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Energy balance and its components: implications for body weight regulation [PDF]

open access: bronze, 2012
Kevin D. Hall   +5 more
openalex   +1 more source

Lactobacillus rhamnosus GG ameliorates osteoporosis in ovariectomized rats by regulating the Th17/Treg balance and gut microbiota structure

open access: gold, 2023
Mengyu Guo   +10 more
openalex   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

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