Results 121 to 130 of about 1,859,491 (323)

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

open access: yesMolecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka   +10 more
wiley   +1 more source

On balances [PDF]

open access: yesJournal of the Franklin Institute
n ...
openaire   +1 more source

Experimental Study on Flexural Performance of Screw Clamping and Welding Joint for Prestressed Concrete Square Piles

open access: yesBuildings
To ensure the connection performance of precast concrete square piles, a screw clamping and welding joint connection is applied to the solid square piles.
Quanbiao Xu   +3 more
doaj   +1 more source

On the non-balanced property of the category of crossed modules in groups [PDF]

open access: yesarXiv, 2003
An algebraic category $\mathcal{C}$ is called balanced if the cotriple cohomology of any object of $\mathcal{C}$ vanishes in positive dimensions on injective coefficient modules. Important examples of balanced and of non-balanced categories occur in the literature. In this paper we prove that the category of crossed modules in groups is non-balanced.
arxiv  

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

Ear Decomposition and Balanced Neighborly Simplicial Manifolds [PDF]

open access: yesarXiv, 2016
We find the first non-octahedral balanced 2-neighborly 3-sphere and the balanced 2-neighborly triangulation of the lens space $L(3,1)$. Each construction has 16 vertices. We show that there exists a balanced 3-neighborly non-spherical 5-manifold with 18 vertices.
arxiv  

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Changes in total and segmental bioelectrical resistance are correlated with whole-body and segmental changes in lean soft tissue following a resistance training intervention

open access: yesJournal of the International Society of Sports Nutrition, 2019
Background Raw bioelectrical values can be used to assess physiological outcomes, though limited information is available concerning the relationships between changes in these values and changes in other variables of interest.
Grant M. Tinsley   +5 more
doaj   +1 more source

A small deformation and modifications of locally conformally balanced manifolds [PDF]

open access: yesarXiv, 2019
We will consider locally conformally balanced manifolds. We prove that a locally conformally balanced condition is not stable under a small deformation. We prove that locally conformally balanced condition is stable under any proper modification. We prove that symmetric products of the Kodaira surface can be resolve to locally conformally balanced ...
arxiv  

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