Results 131 to 140 of about 962,920 (299)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Effect of Respiratory Training combined with Core Stability Training for Children with Spastic Cerebral Palsy

康复学报, 2020
Objective:To observe the effect of respiratory training combined with core stability training on motor function, balance function and daily life ability of children with spastic cerebral palsy.Methods:A total of 74 children with spastic cerebral palsy ...
Binong HU, Kai ZHANG, Fang QI, Chunhua WANG, Wenyin ZHOU, Kun AI, Hong ZHANG   +6 more
doaj  

Balance Sheet Rules and Their Ability to Influence Business Performance

, 2021
In the Czech Republic, balance sheet rules represent well known theory that is recommended to enterprises to follow in order to achieve long-term financial balance and stability.
Nosková, Marta, Taušl Procházková, Petra   +1 more
core  

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Application research progress on virtual reality technology for patients with mild cognitive impairment

Huli yanjiu, 2019
This article summarized the current application of virtual reality(VR)technology for patients with mild cognitive impairment(MCI),and its impact on patients,mainly related to improving cognitive ability,improving balance,enhancing autonomy,improving ...
邹振亚, 刘冉冉, 许翠萍
doaj  

Precision intervention of virtual reality training for balance and gait in Parkinson’s disease: a dose–response meta-analysis

Frontiers in Neurology
BackgroundThis study systematically evaluated the effects of virtual reality training (VRT) on balance ability and functional gait in Parkinson’s disease (PD) patients and used dose–response analysis to quantify optimal intervention parameters, providing
Hailong Wu, Cheng Zhang
doaj   +1 more source

If You Are So Smart, Why Aren't You an Entrepreneur? Returns to Cognitive and Social Ability: Entrepreneurs versus Employees [PDF]

How valuable are cognitive and social abilities for entrepreneurs’ incomes as compared to employees? We answer three questions: (1) To what extent does a composite measure of ability affect an entrepreneur's earnings relative to employees?
Hartog, Joop, van der Sluis, Justin, van Praag, Mirjam   +2 more
core  

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

The relationship between work and non-work support and work-life balance in Taiwan

, 2009
The aim of this study is to explore the relationship between employees' supportive resource (workplace support and non-work support) and their work-life balance in Taiwan.
Chang, Ruby Yi-Ju
core