Results 61 to 70 of about 985,690 (257)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Effects of finger acupressure combined with lower limb rehabilitation training machine on stroke recovery

Frontiers in Neurology
BackgroundStroke is a common acute cerebrovascular disease, and rehabilitation therapy plays a crucial role in the recovery of stroke patients.MethodsIn this retrospective study, we first enrolled 80 stroke patients. These participants were then randomly
Xiaoxue Liu, Feng Zhang, Yanhong Li, Jieqiong Zhao, Yatao Du, Qian Zhang, Weifang Li   +6 more
doaj   +1 more source

The effects of balance training on balance pad and sand on balance and gait ability in stroke patients

Journal of the Korean Society of Physical Medicine, 2016
PURPOSE: The purpose of this study was to determine the effects of balance training on balance pad and sand on balance and gait ability in stroke patients. METHODS: Sixty stroke patients were divided into a Balance Pad group(BPG, N = 20), a Sand group (SG, N = 20) and a Hard Ground group (HGG, N = 20) randomly.
Gui-bin Song, Eun-cho Park
openaire   +2 more sources

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

The effect of olfactory stimuli on the balance ability of stroke patients

Journal of Physical Therapy Science, 2015
[Purpose] The present study attempted to identify the effect of olfactory stimulation on the balance ability of stroke patients. [Subjects] Thirty-three (33 males) stroke patients participated in the study. The stroke patients were divided into three groups: a black pepper oil (BPO) group (n=11), lavender oil (LVO) group (n=11), and distilled water (DW)
Gim, Mi-Na, Lee, Sang-bin, Yoo, Kyung-Tae, Bae, Ji-Young, Kim, Mi-Kyoung, Choi, Jung-Hyun   +5 more
openaire   +3 more sources

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Effect on Movement and Balance Function with Robot Training for Stroke Patients in Lower Limb Rehabilitation

康复学报, 2020
Objective:To observe the effect of lower limb rehabilitation robot training on movement and balance function of stroke patients.Methods:A total of 123 patients with stroke treated in affiliated Zhengzhou central hospital of Zhengzhou university were ...
Zhiyuan WU, Kunbin LI, Shuwei LOU, Xianli YAO, Pingge SUN, Xiaoxing LI   +5 more
doaj  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Effect of Imaging Therapy Combined with Electronic Biofeedback on Stroke

康复学报, 2020
Objective:To investigate the clinical application value of imaging therapy combined with electronic biofeedback in the improvement of lower extremity motor function, walking ability, activities of daily living and balance ability in stroke patients ...
Xiaohui ZHAO, Linli JIANG, Fengjiao WANG, Jun WANG, Fei XU   +4 more
doaj