Results 81 to 90 of about 1,250,952 (308)

The roles of melanin-concentrating hormone in energy balance and reproductive function: are they connected?

open access: yes, 2013
Melanin concentrating hormone (MCH) is an anabolic neuropeptide with multiple and diverse physiologic functions including a key role in energy homeostasis.
Murray, J.F., Cunliffe, A., Naufahu, J.
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Work-life balance: the impact of policy and practice on the human resource function

open access: yes, 2005
As organizations increasingly become subjected to the forces of globalization, pressure to increase competitiveness and with it the demands on people to serve their businesses with drive and commitment become even stronger.
Shortland, S.
core  

Home-based virtual reality balance training and conventional balance training in Parkinson's disease: A randomized controlled trial

open access: yes, 2017
Background/Purpose: Virtual reality has the advantage to provide rich sensory feedbacks for training balance function. This study tested if the home-based virtual reality balance training is more effective than the conventional home balance training in ...
Yang, Wen-Chieh;Wang, Hsing-Kuo;Wu, Ruey-Meei;Lo, Chien-Shun;Lin, Kwan-Hwa   +1 more
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Association of Increased Nasal Fluids-Serum Concordance of Protein Profile with Prognosis in Nasal Polyps

open access: yesJournal of Inflammation Research
Yilin Hou,1– 5 Lin Sun,2– 5 Changhui Chen,2– 5 Mengqi Su,6 Shimin Lai,2– 5 Yan Yan,2– 5,7 Jieying Yan,2– 5 Rongjian Zhan,2– 5 Yongjin Su,1 Weiqiang Yang,1 Yi Wei,2– 5 Weiping Wen,2– 5,7 Hongyi Hu1 1Otorhinolaryngology, Peking University Shenzhen Hospital,
Hou Y   +12 more
doaj  

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Research progress on balance function training method for the elderly

open access: yesHuli yanjiu, 2016
It reviewed the balance function training methods for the elderly from the aspects of muscle strength training,body sensory training,body vibration balance training and cognitive function training.It put forward that problems in the domestic research ...
万文洁, 瞿强, 徐燕
doaj  

Efficacy and safety of using a unilateral lower limb exoskeleton combined with conventional treatment in post-stroke rehabilitation: a randomized controlled trial

open access: yesFrontiers in Bioengineering and Biotechnology
IntroductionThe incidence of hemiplegia caused by stroke is high. In particular, lower limb dysfunction affects the daily activities of patients, and lower limb robotic devices have been proposed to provide rehabilitation therapy to improve balance ...
Ying Jin   +6 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

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