Results 121 to 130 of about 592,802 (306)

Mineral resource dilemma: how to balance the interests of government, local communities and abiotic nature. [PDF]

Int J Environ Res Public Health, 2014
Nikitina N.
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Legal Protection Mechanisms for Copyright of Artificial Intelligence-Generated Content

Journal of Intellectual Property
With advances in quality productive forces, new types of intellectual achievements, such as Artificial Intelligence-Generated Content (AIGC), have emerged on a large scale.
Tingting Gao
doaj   +1 more source

"Europe's External Energy Policy: Between Geopolitics and the Market." CEPS Working Document No. 278, November 2007 [PDF]

, 2007
While energy security has gradually been incorporated into the EU's foreign policy calculus, the declared approach of extending a nexus of 'marketgovernance' energy norms has been realised only to a limited extent.
Youngs, Richard.
core  

Shifting The Balance Achieved by the Abduction Convention: The Contrasting Approaches of the European Court of Human Rights and the European Court of Justice

, 2011
First paragraph: The 1980 Hague Convention on the Civil Aspects of International Child Abduction (“the Abduction Convention”) seeks to secure the prompt return of children in cases of wrongful removal or retention. It operates on the assumption that this
Beaumont, Paul, Walker, Lara, Lara Walker (163199), Lara Walker, Paul Beaumont, Paul Beaumont (3383381)   +5 more
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Principle of balance of interests in state coercion in civil law / A. М. Yafremenka

, 2016
Ефременко, Е. М. Принцип баланса интересов в системе мер государственного принуждения в гражданском праве / Е. М. Ефременко // Вестник Академии МВД Республики Беларусь. - 2016. - № 2. - С.
Ефременко, Е. М.
core  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Current issues of the balance between economic and environmental interests in the territorial planning process

, 2012
Darbā tiek aplūkoti aktuālie jautājumi teritorijas plānošanas procesā, sabalansējot ekonomiskās intereses ar vides aizsardzības interesēm, kas Latvijas Republikas Satversmē tiek aizsargātas kā tiesības uz īpašumu un tiesības uz labvēlīgu vidi.
Metāls, Gints
core  

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source