Results 41 to 50 of about 590,131 (312)
Pakistan’s Journey from Imbalance to Balance of Power (1947-1998)
, 2023 India and Pakistan are two nuclear-armed rivals in South Asia. Historicallythey have gone to full-fledged and small-scale wars. Power asymmetry hasbeen the main cause of war.
Naseer Naseer; Lecturer of International Relations at the Department of Humanities,COMSATS, Institute of Information Technology Rawalpindi - Pakistan. +1 more
core
Participation of distributed generation in balance management [PDF]
, 2009 Distributed generation is not yet considered to participate in balance management in power systems. Low marginal costs and poor predictability make them less attractive for this application.
Frunt, J Jasper +11 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Where is the World Heading? The Chronicle of Grand Transformation [PDF]
Современная Европа, 2023 Alexey A. Gromyko
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
HUBUNGAN ARAB SAUDI DAN QATAR PADA KONFLIK DI KAWASAN TIMUR TENGAH TAHUN 2017
Siyar Journal, 2022 Didalam artikel ini menjelaskan mengenai konflik yang terjadi antara Arab Saudi dan Qatar pada tahun 2017.Konflik tersebut berujung pada pemutusan hubungan diplomatik oleh Arab Saudi terhadap Qatar.Aliansi yang dilakukan oleh Qatar dengan Iran ...
Muh Ghozali Rahman
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source