Results 81 to 90 of about 590,131 (312)

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

EVALUATION OF THE INTERNATIONAL SYSTEM IN RUSSIAN OFFICIAL DISCOURSE AND ACADEMIC ANALYSIS

Vestnik MGIMO-Universiteta, 2016
The article draws a comparison between Russian official and expert foreign policy discourses, focusing on representations of the power balance and relations between major states as the defining features of international system.
I. A. Istomin
doaj   +1 more source

The effects of strength and power training on single-step balance recovery in older adults: a preliminary study

, 2014
Derek N Pamukoff,1 Eric C Haakonssen,1 Joseph A Zaccaria,1 Michael L Madigan,2 Michael E Miller,3 Anthony P Marsh1 1Department of Health and Exercise Science, Wake Forest University, Winston-Salem, NC, USA; 2Department of Engineering Science and ...
Madigan ML, Pamukoff DN, Zaccaria JA, Haakonssen EC, Miller ME, Marsh AP   +5 more
core  

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Shift in the regional balance of power as a precondition for Azerbaijan's military intervention in Nagorno-Karabakh in 2020 [PDF]

Srpska Politička Misao
The Second Nagorno-Karabakh War of 2020 decisively influenced the regional security architecture of the South Caucasus and the fate of the protracted Azerbaijani-Armenian conflict over the status of this mountainous enclave.
Preradović Nikola, Bogićević Aleksandar   +1 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

ECONOMIC REALITIES AND PROSPECTS OF BRICS AND G7 [PDF]

Strategii Manageriale, 2013
In the context of the trends changing the balance of forces in the global economy, this paper mainly highlights the economic, political and strategic influences that the emerging countries, members of the BRICS group, undertake worldwide.
Georgiana, Mîndreci, Ioana-Iulica, Mihai   +1 more
doaj  

Sino-Pakistan Maneuvering to Balance the Power in South Asia

, 2020
With the advent of nuclear weapons escalation between India and Pakistan is less likely. Kargilcrisis (1999) is the testament that nuclear deterrence in South Asia got credibility.
Dr. Rizwan Naseer; COMSATS Institute of Information Technology (CIIT) Islamabad,, Dr. Musarat Amin; Fatima Jinnah Women University Rawalpindi,   +1 more
core  

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source