Results 121 to 130 of about 3,136,097 (297)

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Role of the domestic market and export-expansion development in economic growth” [PDF]

open access: yesInternational Economic Policy, 2007
The author examines the issue of domestic market expansion within the context of the country’s economic growth. With the assistance of the Kalman filter she analyzes the effect of internal and external factors on the balance of external accounts ...
Myroslava Munko
doaj  

APROXIMACIÓN TEÓRICA AL BALANCE SOCIAL

open access: yesContabilidad y Auditoría, 2003
Fil: Sánchez Henriquez, Jorge Alejandro. Universidad de Santiago de Chile. Chile.
openaire   +2 more sources

Balance social, función del cooperativismo.

open access: yes, 2022
El balance social le ofrece a la cooperativa una amplia serie de posibilidades, instrumentos y herramientas que hacen de esta técnica un elemento particularmente útil e importante en su labor diaria, ya que le facilita un diagnóstico total de la empresa, de su situación, de sus públicos, de sus expectativas, satisfacciones, necesidades, etc. lo cual es
Fernández Villa, María Isabel   +1 more
openaire   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Ukraine’s trade and economic priorities in the Black sea economic cooperation [PDF]

open access: yesInternational Economic Policy, 2013
The article is devoted to the substantiation of trade and economic priorities of Ukraine’s integration into the Black Sea Economic Cooperation (BSEC). The country’s integration options have been analyzed including the Western European vs.
Andriy Goncharuk, Iryna Troyan
doaj  

Welfare Effects of Salary Caps in Sports Leagues with Win-Maximizing Clubs [PDF]

open access: yes
This paper studies the welfare effect of a percentage-of-revenue salary cap in a European context with win-maximizing clubs. It shows that a percentage-of-revenue cap increases competitive balance and decreases the overall salary payments in the league ...
Alexander Rathke   +3 more
core  

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

The Efficiency Of Ukraine’s Stock Market [PDF]

open access: yesInternational Economic Policy, 2006
The article is devoted to the study of the efficiency of Ukraine’s stock market based on the efficient market hypothesis (EMH) which assumes that the price of a financial instrument completely reflects all the information about a given asset.
Adilya Batroshyna
doaj  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

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