Results 131 to 140 of about 530,973 (307)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

The assessment of posture and balance post-stroke

open access: yes, 2002
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Physiotherapy for people with stroke has been found to be beneficial but details of the most effective interventions are unclear. Further development of the
Tyson, Sarah F, Tyson, Sarah F.
core  

El balance social como instrumento de políticas públicas orientadas al desarrollo socioeconómico regional [PDF]

open access: yes, 2019
En el marco de la Resolución Técnica número 36 (RT 36) de la Federación de Consejos Profesionales de Ciencias Económicas de la República Argentina, el presente proyecto de investigación busca analizar al Balance Social y sus Memorias de Sostenibilidad ...
Martínez, Julio Alejandro Nicolás   +9 more
core   +1 more source

Global modification of the market competitive mechanisms [PDF]

open access: yesInternational Economic Policy, 2010
In the article there were studied the phenomenon of the global economy, preconditions and factors of its establishment. It demonstrates that mechanisms of the global market transform the traditional subject disposition, forms and competition methods ...
Dmytro Lukianenko, Olena Titova
doaj  

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Forming of Sustainable City Competitiveness in the PRC [PDF]

open access: yesInternational Economic Policy, 2017
The article describes theoretical principles of international competitiveness of cities. The main methodological grounds of modern models of countries sustainable competitive development are studied. Taking into account the key trends in globalization,
Shvydanenko Oleg, Antonyuk Bogdan
doaj  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Socioeconomic Development of Ukraine’s agricultural sector in the context of foreign economic strategic choices [PDF]

open access: yesInternational Economic Policy, 2006
This article examines the preconditions and specifics for developing Ukraine’s foreign economic strategy and generalizes the experience of other countries in the impact of their strategies on their integration into the European Union and the development ...
Olena Dyachenko
doaj  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

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