Results 121 to 130 of about 530,973 (307)
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Ukraine’s trade and economic priorities in the Black sea economic cooperation [PDF]
International Economic Policy, 2013 The article is devoted to the substantiation of trade and economic priorities of Ukraine’s integration into the Black Sea Economic Cooperation (BSEC). The country’s integration options have been analyzed including the Western European vs.
Andriy Goncharuk, Iryna Troyan
doaj
Balance social : Indicadores para balance social de cooperativas de trabajo
, 2021 Facultad de Ciencias ...
Acosta, Paola Cecilia +3 more
openaire +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Competitive balance in complex professional sports leagues [PDF]
, 2008 Competitive balance is seen as crucial to the viability of professional sports leagues, and it has been a central concern of sports economists, industry practitioners and fans. But the concept is complex and ill-defined. The theoretical approach in this
Kringstad, Morten
core
The Efficiency Of Ukraine’s Stock Market [PDF]
International Economic Policy, 2006 The article is devoted to the study of the efficiency of Ukraine’s stock market based on the efficient market hypothesis (EMH) which assumes that the price of a financial instrument completely reflects all the information about a given asset.
Adilya Batroshyna
doaj
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Diferencia entre auditoria social y balance social
, 2017 El presente trabajo de investigación tiene como propósito establecer las diferencias entre Auditoria Social y balance social. Se destaca que la auditoria social es una rama de la contabilidad que nace para mantener la convicción en los procesos al ...
Mendoza Cárdenas, María Alejandra
core
Sustainability of the Actuarial Balance: Turkey’s Experience Between 1972-2013 [PDF]
, 2019 This study is designed based on a two-part hypothesis that (1) active/passive ratios, which are the most commonly used criteria in measuring financial balances of social security institutions in Turkey, are a good indicator and that (2) the 1972-2013 ...
Bayraktar, Yüksel, Yaşarlar, Yaşar
core +1 more source
Conditions and Factors Forming Investment Attractivenes of Eastern Europe Countries [PDF]
International Economic Policy, 2017 In the article, factors of influence and conditions of investment attractiveness in the Eastern European countries and Ukraine are characterized on the basis of the analysis of the relevant statistical factor, the main features of the investment ...
Horna Maryna. +2 more
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