Results 121 to 130 of about 6,688 (279)

Cellular Morphometric Analysis (CellMorph)—a comprehensive imaging‐based tool for quantifying cellular phenotype heterogeneity and dynamics across biological processes

open access: yesThe FEBS Journal, EarlyView.
CellMorph is a groundbreaking tool that allows researchers to analyze multiple features from single cells, including cell size and shape, cytosolic staining and subcellular texture, nuclear staining, and morphometry. By evaluating images from both bright‐field and fluorescence microscopy, it also tracks changes in living cells during key processes such
Henrique Quaiato de Oliveira   +16 more
wiley   +1 more source

Targeted, receptor‐mediated delivery of a masked d‐amino acid cell‐penetrating peptide for cell‐specific phototoxicity

open access: yesThe FEBS Journal, EarlyView.
A targeted phototoxic peptide selectively accumulates in cells expressing chemokine‐like receptor 1 (CMKLR1). Phototoxicity of the native peptide is low, but cleavage by lysosomal protease cathepsin B releases a 6‐tetramethylrhodamine (TMR) labeled nona‐ᴅ‐arginine which mediates lysosomal rupture and cell death upon irradiation.
Moritz List   +2 more
wiley   +1 more source

Prospective Trial of Radiofrequency Catheter Ablation of High Dominant Frequencies After Pulmonary Vein Isolation in Non‐Paroxysmal Atrial Fibrillation (PAD‐AF Trial): A Multicenter, Randomized Clinical Trial

open access: yesJournal of Cardiovascular Electrophysiology, EarlyView.
In persistent AF, adjunctive dominant frequency‐guided ablation after pulmonary vein isolation did not significantly improve outcomes. Limited overlap between high‐frequency sites and low‐voltage areas suggests functional–structural dissociation, while right atrial low‐voltage burden predicts recurrence.
Koji Kumagai   +10 more
wiley   +1 more source

Development of sleepiness in professional truck drivers: Real‐road testing for driver drowsiness and attention warning (DDAW) system evaluation

open access: yesJournal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary All new vehicle types within the European Union must now be equipped with a driver drowsiness and attention warning system starting from 2022. The specific requirements for the test procedure necessary for type approval are defined in the Annex of EU Regulation C/2021/2639.
Christer Ahlström, Anna Anund
wiley   +1 more source

Rotated Half-Mode Substrate Integrated Waveguide and other Planar Integrated Structures [PDF]

open access: yes, 2015
High data rate communication channels are becoming more and more integrated into our increasingly technological society. Substrate Integrated Waveguides (SIW) are one planar solution available to the microwave engineer, offering a low-loss and low ...
Farrall, Andrew J
core  

Novel murine closed‐loop auditory stimulation paradigm elicits macrostructural sleep benefits in neurodegeneration

open access: yesJournal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Boosting slow‐wave activity (SWA) by modulating slow waves through closed‐loop auditory stimulation (CLAS) might provide a powerful non‐pharmacological tool to investigate the link between sleep and neurodegeneration. Here, we established mouse CLAS (mCLAS)‐mediated SWA enhancement and explored its effects on sleep deficits in neurodegeneration,
Inês Dias   +5 more
wiley   +1 more source

Quantifying Cortical Maturational Aspects During Different Vigilance States in Preterm Infants by Advanced EEG Analysis

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT Preterm birth is a significant risk factor for atypical neurodevelopment, yet early electrophysiological markers of brain maturation are still lacking. Non‐invasive electroencephalographic (EEG) monitoring of cortical maturation in these patients holds promise as a tool for neurodevelopmental prediction.
Gaia Burlando   +9 more
wiley   +1 more source

Design of Millimeter-wave Switches and Bandpass Filter-Integrated Switches

open access: yes, 2007
This dissertation includes the design of millimeter-wave switches and band-pass filter integrated switches for RF front end applications. The first part of the dissertation focuses on the design of millimeter-wave switches.
趙世峰, Chao, Shih-Fong
core  

Sleep Preserves, Wake Differentiates: Strength‐Dependent Forgetting of Declarative Memories Across the Retention Interval

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT Sleep benefits memory, but the extend to which this benefit depends on initial memory strength remains heavily debated. We examined whether sleep preferentially stabilises weakly versus strongly encoded declarative memories, and whether classical sleep oscillations contribute to this effect.
M. Schabus, M. S. Ameen, D. P. J. Heib
wiley   +1 more source

Strong and Weak Episodic Memories Are Shaped by Multiple Cycles of NREM Spindles and REM Alpha Bursts

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT Prior research has built up the notion that non‐rapid eye movement sleep (NREM) and rapid eye movement sleep (REM) are separately important for specific types of memory. However, growing evidence suggests that these sleep stages work in conjunction to jointly shape memory.
A. E. Shuster   +2 more
wiley   +1 more source

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