Results 51 to 60 of about 17,180 (267)
Resistance of Balanced Incomplete Block Designs
The Annals of Statistics, 1975 Hedayat and John (1974) studied the case of resistance of a balanced incomplete block design (BIBD) to the removal of one treatment. They showed that a necessary and sufficient condition for a BIBD to be resistant (that is, retain its variance balance) upon removal of a single treatment is that the two proper subdesigns created by this removal be BIBDs.
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RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
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Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
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Missing Data Imputation in Balanced Construction for Incomplete Block Designs
MathematicsObservational data with massive sample sizes are often distributed on many local machines. From an experimental design perspective, investigators often desire to identify the effect of new treatments (even ML algorithms) on many blocks of experimental ...
Haiyan Yu +3 more
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Scientia Agricola, 1996 O objetivo do presente trabalho foi desenvolver uma metodologia adequada para análise intrablocos de experimentos em parcelas subdivididas quando os tratamentos primários estão dispostos em uma estrutura de delineamento em blocos incompletos parcialmente
A.R. de MORAIS, M.C.S NOGUEIRA
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Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
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An Inequality for Balanced Incomplete Block Designs
The Annals of Mathematical Statistics, 1961 For a resolvable balanced incomplete block design, R. C. Bose [1] obtained the inequality $b \geqq v + r - 1$, and P. M. Roy [2] and W. F. Mikhail [3] proved this inequality without the assumption of resolvability, but with the weaker assumption that $v$ is a multiple of $k$. In this note an alternative and simpler proof of Roy's theorem is given.
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Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce +72 more
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On the Structure of Balanced Incomplete Block Designs
The Annals of Mathematical Statistics, 1952 In this paper there are developed for the first time analytical methods for the investigation of the structure of unsymmetrical balanced incomplete block designs. Two unsymmetrical balanced incomplete block designs are proved to be impossible, and for such designs in general, inequalities are found for the number of treatments common to two blocks.
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A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling +16 more
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