A Whole‐Head Finite Element Model for Electrical Neuromodulation via Visual Brain‐Machine Interfaces
A multimodal, personalized head model is presented that integrates the entire visual pathway with surrounding tissues to simulate electrical stimulation of the optic nerve. In vivo validation in humans and goats, plus systematic component‐elimination analysis, demonstrates the high accuracy of the comprehensive model.
Shengjian Lu +12 more
wiley +1 more source
Erector spinae plane block reduces postoperative nausea and vomiting: a systematic review and meta-analysis of 44 randomized trials. [PDF]
Zhao C, Zhu M, Jian J, Zeng J.
europepmc +1 more source
Deep Contrastive Learning for High‐Throughput Prediction of Drug Resistance Mutations from Sequences
This study presents DeepMutDTA, a deep learning framework aimed at predicting mutation‐induced changes in protein‐drug interactions and prioritizing variants potentially linked to drug resistance. Trained on large‐scale data, it incorporates SimSiam‐MuTF, a label‐aware contrastive fine‐tuning strategy that encourages separation between WT and MT ...
Xiaowen Hu +7 more
wiley +1 more source
SEU-Hardened High-Speed SRAM Design with Self-Refresh and Adjacent-Bit Error Correction. [PDF]
Li T, Tian J, Qi J.
europepmc +1 more source
ABSTRACT Inflammatory bowel disease (IBD) is characterized by dysregulated T cell responses. RNA helicases, including DExD‐box helicase 21 (DDX21), are pivotal in RNA metabolism, but their role in T cell‐mediated pathology during IBD remains unclear. Here, we demonstrate that DDX21 expression in CD4+ T cells correlates with cell cycle and translation ...
Yujuan Zhang +11 more
wiley +1 more source
Multimodal analgesia strategies enhance postoperative recovery and mitigate inflammatory responses in women undergoing elective surgery for endometrial cancer: a retrospective cohort study. [PDF]
Tang Y, He Y, Yang H, Li H, Mao A.
europepmc +1 more source
This study presents a human Bone (and Bone Marrow)‐on‐a‐Chip model based on native human bone scaffolds and autologous cells. Dynamic perfusion and sequential cell seeding replicate the physiological bone remodeling process in vitro, enabling the long‐term culture of functional, mature bone marrow immune subpopulations.
Nina Stelzer +17 more
wiley +1 more source
LVCA-Net: Lightweight LiDAR Semantic Segmentation for Advanced Sensor-Based Perception in Autonomous Transportation Systems. [PDF]
Gong Y, Huang Y, Bao L, Wang J.
europepmc +1 more source
Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green +15 more
wiley +1 more source
Evaluating student satisfaction and self-confidence across a scaffolded simulation curriculum in undergraduate nursing education. [PDF]
Übelacker A +4 more
europepmc +1 more source

