Results 21 to 30 of about 5,985 (229)

Anaerobic Co-Digestion of Swine Wastewater, Cheese Whey and Organic Waste: Performance Optimization Through Mixture Design

Biomass
Anaerobic co-digestion of agro-industrial and municipal biowastes can enhance methane production, but the optimal mixture depends on nonlinear interactions among substrates.
Verónica Córdoba, Gianluca Ottolina
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Coupling effects of drip irrigation frequency and nitrogen rate on the growth, development, and economic benefits of Sea Island cotton in Southern Xinjiang

Agricultural Water Management
Inefficient water and nitrogen management significantly constrains the yield potential of Sea Island cotton in arid regions. Field experiments in southern Xinjiang, China (2022–2023) evaluated the interactive effects of irrigation frequency (F5, F7, and ...
Qiuping Fu, Zhiduo Dong, Yang Pan, Wenzheng Tang, Yingjie Ma, Tong Qi, Pingan Jiang, Quanjiu Wang   +7 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

The Multi‐Functional Third Acceptor Realizes the Synergistic Improvement in Photovoltaic Parameters and the High‐Ratio Tolerance of Ternary Organic Photovoltaics

Advanced Science
The ternary strategy proves effective for breakthroughs in organic photovoltaics (OPVs). Elevating three photovoltaic parameters synergistically, especially the proportion‐insensitive third component, is crucial for efficient ternary devices.
Yuhao Liu, Lingling Zhan, Zhongjie Li, Hang Jiang, Huayu Qiu, Xiaokang Sun, Hanlin Hu, Rui Sun, Jie Min, Jinyang Yu, Weifei Fu, Shouchun Yin, Hongzheng Chen   +12 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

CONSTRUCTION METHOD OF A-OPTIMAL CHEMICAL BALANCE WEIGHING DESIGNS

Acta Universitatis Lodziensis. Folia Oeconomica, 2015
Here, we study the design in that we determine unknown measurements of p objects by used of n measurement operations. For that reason we consider the chemical balance weighing design under assumption that the measurement errors are uncorrelated and they ...
Bronisław Ceranka, Małgorzata Graczyk
doaj  

Symmetric balanced ternary designs with ϱ1 = 1 or 2

Aequationes Mathematicae, 1994
A balanced ternary design is a collection of blocks containing various points 0, 1 or 2 times and such that the size of the blocks and the number of occurrences of any point or any pair of distinct points simultaneously in the same block are constants.
openaire   +2 more sources