Results 31 to 40 of about 5,985 (229)

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Physico-mechanical and microstructural investigation of a fly ash-based geopolymer and an inorganic waste blend-reinforced fly ash-based geopolymer pastes: A comparative study

open access: yesNext Materials
The high carbon emissions associated with ordinary Portland cement production have intensified the search for sustainable and low-impact alternatives in the construction sector.
Badr Aouan   +7 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

ON D-OPTIMAL CHEMICAL BALANCE WEIGHING DESIGNS

open access: yesActa Universitatis Lodziensis. Folia Oeconomica, 2015
The paper deals with the problem of determining the chemical balance weighing designs satisfying the criterion of D-optimality under assumption that the measurement errors are equal correlated and they have the same variances.
Bronisław Ceranka, Małgorzata Graczyk
doaj  

Fast Addition Using Balanced Ternary Counters Designed with CMOS Semi-Floating Gate Devices [PDF]

open access: yes37th International Symposium on Multiple-Valued Logic (ISMVL'07), 2007
This paper presents ternary counters using balanced ternary notation. The balanced ternary counters can replace binary full adders or counters in fast adder structures. The circuits use recharged CMOS semi-floating gate (RSFG) devices. By using balanced ternary notation, it is possible to build balanced ternary addition circuits, which can add both ...
Henning Gundersen, Yngvar Berg
openaire   +2 more sources

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

A family of balanced ternary designs with block size four [PDF]

open access: yesBulletin of the Australian Mathematical Society, 1986
This paper shows the existence of an infinite family of cyclic balanced ternary designs where the block size is 4, the index 2 and each block contains precisely one repeated element.
openaire   +4 more sources

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

Constructions of balanced ternary designs based on generalized Bhaskar Rao designs

open access: yesJournal of Statistical Planning and Inference, 1993
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Sarvate, Dinesh G., Seberry, Jennifer
openaire   +4 more sources

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