Results 231 to 240 of about 484,891 (284)

Digoxin Alleviates Osteoarthritis by Inhibiting Macrophage Extracellular Trap Formation via Disruption of the LSP1‐SOD1 Interaction

open access: yesAdvanced Science, EarlyView.
Synovial macrophages in osteoarthritis upregulate LSP1, which directly binds and inhibits SOD1, triggering a redox imbalance that activates both NOX and mitochondrial ROS pathways. This cascade drives the release of macrophage extracellular traps (METs), causing chondrocyte damage and disease progression.
Yankai Pan   +9 more
wiley   +1 more source

SPIRAL: A versatile online single time-point circadian analysis platform for rice. [PDF]

open access: yesSci Adv
Shi Y   +11 more
europepmc   +1 more source

Analytical Prediction of Critical Transitions in Oscillator Networks With Non‐Local Links

open access: yesAdvanced Science, EarlyView.
An analytical framework reveals how global coupling, second‐harmonic strength, noise, and network structure govern oscillator‐based Ising dynamics. Spectral reduction predicts stability boundaries, while Fokker–Planck analysis captures one‐ to two‐cluster transitions and identifies conditions favoring low‐energy configurations.
Qiang Li   +5 more
wiley   +1 more source

Transgressive Segregation, Reciprocal Effects and Multi-Trait Selection in an F2 Bread Wheat Diallel Under Speed Breeding. [PDF]

open access: yesPlants (Basel)
Yorulmaz L   +6 more
europepmc   +1 more source

Immune Biomarkers of Islet Transplant Rejection Revealed by Synthetic Immunological Niche

open access: yesAdvanced Science, EarlyView.
A subcutaneous synthetic immunological niche (IN) enables serial, minimally invasive monitoring of immune responses after islet transplantation. Flow cytometry and transcriptomic profiling of the IN reveal immune‐cell programs associated with graft acceptance and distinct types of rejection.
Jyotirmoy Roy   +8 more
wiley   +1 more source

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