Results 241 to 250 of about 484,891 (284)

β‐Adducin Restrains PLA2G4A‐Dependent Lysosomal Membrane Permeabilization and Neuronal Death in Ischemic Stroke

Advanced Science, EarlyView.
This study identifies β‐adducin as a regulator of lysosomal integrity in ischemic neurons. Ischemia‐associated FTO loss increases m6A modification and destabilizes Add2 mRNA, reducing β‐adducin expression and promoting PLA2G4A accumulation at lysosomes.
Hui‐qin Li, Pin‐yi Liu, Dan Wu, Fei‐yu Ma, Yi Bai, Sheng‐nan Xia, Hai‐yan Yang, Xin‐yu Bao, Yun Xu, Xiang Cao   +9 more
wiley   +1 more source

Uncovering species- and drug-class-specific antimicrobial resistance mechanisms from large-scale whole-genome sequencing data using discordance analysis and machine learning. [PDF]

Brief Bioinform
Cheon NJ, Cuong Nguyen X, Unno T.
europepmc   +1 more source

Targeted Therapy, Immunotherapy, and Molecular Testing in Advanced Solid Tumors: A Medicare Analysis. [PDF]

Cancer Med
Baser O, Sun Y.
europepmc   +1 more source

Dissecting the propensity of RIM1 subdomains to form phase condensates. [PDF]

Sci Rep
Kersten L, Galkov M, Nemcova P, Mostafa AHD, Quatraccioni A, Dietrich D, Schoch S.   +6 more
europepmc   +1 more source

Post-translational modifications as a regulatory code for tau function in health and disease. [PDF]

Front Dement
Nordbeck AJ, Sharma B, Garcia CA, Tseng JH.   +3 more
europepmc   +1 more source

Electrochemically Induced Structural Evolution to Generate Optimized High-Entropy-Alloy Electrocatalysts for Ethanol Oxidation. [PDF]

Angew Chem Int Ed Engl
Hsiao YC, Jang H, Chang CW, Lin JT, Lee KF, Gardner AM, Potter RJ, Neale AR, Hardwick LJ, Lin KH, Yang TH, Cowan AJ.   +11 more
europepmc   +1 more source

crRNA Truncation Minimizes <i>cis</i>-Cleavage for Universal One-Pot RPA-CRISPR-Cas12a Detection with Attomolar Sensitivity. [PDF]

JACS Au
Zhang W, Zhou Z, Feng X, Feng T, Liu X, Lin Q, Fan W, Liu C.   +7 more
europepmc   +1 more source

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A note on closed-loop balanced truncation

IEEE Transactions on Automatic Control, 1996
The closed-loop balanced truncation (CLBT) is discussed. CLBT performs truncation on a realization of the controller in which the parts \(P_c\) and \(Q_c\) of the controllability and observability gramians that correspond to the controller states are balanced; as a result the closed-loop transfer function is changed as little as possible.
B de Moor
exaly   +4 more sources

Properties of Frequency Weighted Balanced Truncation Techniques [PDF]

2007 IEEE International Conference on Automation Science and Engineering, 2007
In this paper, we derive interesting conditions under which the frequency weighted balanced truncation techniques: Enns' technique, Lin and Chiu's technique, Wang et al's technique as well as Varga and Anderson's technique are equivalent.
Shafishuhaza Sahlan, Abdul Ghafoor 0002, Victor Sreeram   +2 more
openaire   +3 more sources