Results 51 to 60 of about 484,891 (284)

Model Compression Method for S4 With Diagonal State Space Layers Using Balanced Truncation

IEEE Access
To implement deep learning models on edge devices, model compression methods have been widely recognized as useful. However, it remains unclear which model compression methods are effective for Structured State Space Sequence (S4) models incorporating ...
Haruka Ezoe, Kazuhiro Sato
doaj   +1 more source

On Frequency-Weighted Extended Balanced Truncation

CoRR
8 pages, conference ...
Sribalaji Coimbatore Anand, Henrik Sandberg   +1 more
openaire   +2 more sources

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Model Reduction of Parametric Differential-Algebraic Systems by Balanced Truncation

Mathematical and Computer Modelling of Dynamical Systems
We deduce a procedure to apply balanced truncation to parameter-dependent differential-algebraic systems. For that we solve multiple projected Lyapunov equations for different parameter values to compute the Gramians that are required for the truncation ...
Jennifer Przybilla, Matthias Voigt
doaj   +1 more source

A New Reduced-Order Implementation of Discrete-Time Fractional-Order PID Controller

IEEE Access, 2022
This paper presents a new method for computationally effective implementation of a discrete-time fractional-order proportional–integral–derivative (FOPID) controller.
Rafal Stanislawski, Marek Rydel, Zhixiong Li   +2 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Balanced truncation via tangential interpolation

Journal of Computational and Applied Mathematics
This paper examines the construction of rth-order truncated balanced realizations via tangential interpolation at r specified interpolation points. It is demonstrated that when the truncated Hankel singular values are negligible-that is, when the discarded states are nearly uncontrollable and unobservable-balanced truncation simplifies to a bi ...
Umair Zulfiqar, Qiu-Yan Song, Zhi-Hua Xiao, Victor Sreeram   +3 more
openaire   +2 more sources

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

On stochastic balancing related model reduction [PDF]

, 2000
We propose a general method based on the balanced stochastic truncation (BST) approach for the model reduction of stable linear systems. The new method relies on a recent general inner-outer factorization result and extends the applicability of the BST ...
A. Varga, Varga, Andras
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