Results 61 to 70 of about 484,891 (284)

On stability and model order reduction of perturbed nonlinear neural networks [PDF]

open access: yes, 2008
In this paper, the qualitative theory of large-scale dynamical systems is surveyed. In particular, the focus is the Hopfield Neural networks both with and without perturbations.
G. G. Grahovski   +3 more
core   +3 more sources

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

A Residual Approach for Balanced Truncation Model Reduction (BTMR) of Compartmental Systems

open access: yesBulletin of Computational Applied Mathematics, 2014
This paper presents a residual approach of the square root balanced truncation algorithm for model order reduction of continuous, linear and time-invariante compartmental systems.
William La Cruz
doaj  

Robust controller design for speed regulation of a flexible wind turbine [PDF]

open access: yesEAI Endorsed Transactions on Energy Web, 2019
The complexity of large wind turbines increases due to fatigue, aerodynamics, structural flexibility and wind turbulence which lead to uncertainties in the wind turbine model. Hence, a robust controller is necessary to deal with these uncertainties.
N.V.A. Ravikumar, G. Saraswathi
doaj   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

open access: yesFEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez   +4 more
wiley   +1 more source

Controller Reduction of Parameter Dependent Systems [PDF]

open access: yesITB Journal of Engineering Science, 2004
This paper proposes a controller reduction of linear parameter dependent systems. A measure of the degradation is derived for the parameter dependent closed-loop performance caused by applying the reduced-order parameter dependent controller.
Widowati   +2 more
doaj  

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

open access: yesFEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen   +8 more
wiley   +1 more source

Empirical Reduced-Order Modeling for Boundary Feedback Flow Control

open access: yesJournal of Control Science and Engineering, 2008
This paper deals with the practical and theoretical implications of model reduction for aerodynamic flow-based control problems. Various aspects of model reduction are discussed that apply to partial differential equation- (PDE-) based models in general.
Seddik M. Djouadi   +2 more
doaj   +1 more source

A symmetry approach for balanced truncation of positive linear systems [PDF]

open access: yes2012 IEEE 51st IEEE Conference on Decision and Control (CDC), 2012
We consider model order reduction of positive linear systems and show how a symmetry characterization can be used in order to preserve positivity in balanced truncation. The reduced model has the additional feature of being symmetric.
Christian Grussler, Tobias Damm
openaire   +2 more sources

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu   +21 more
wiley   +1 more source

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