Results 51 to 60 of about 1,542,707 (296)

Recent and Ancient Signature of Balancing Selection around the S-Locus in Arabidopsis halleri and A. lyrata [PDF]

open access: yes, 2012
Balancing selection can maintain different alleles over long evolutionary times. Beyond this direct effect on the molecular targets of selection, balancing selection is also expected to increase neutral polymorphism in linked genome regions, in inverse ...
Castric, Vincent   +5 more
core   +3 more sources

‘They Need to Hear You Say It’: Healthcare Professionals’ Perspectives on Barriers and Enablers to End‐of‐Life Discussions With Adolescents and Young Adults With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee   +9 more
wiley   +1 more source

The potential of the anti-hegemonic coalition [PDF]

open access: yesPolitika nacionalne bezbednosti
The authors consider the potential of a loose coalition in curbing US global influence, ie. the implications of its formation and strengthening on the final establishment of multipolarity.
Obradović Zoran, Mihajlović Dejan
doaj   +1 more source

Balancing lists: a proof pearl [PDF]

open access: yes, 2014
Starting with an algorithm to turn lists into full trees which uses non-obvious invariants and partial functions, we progressively encode the invariants in the types of the data, removing most of the burden of a correctness proof.
C. Okasaki, E.W. Myers, L.J. Guibas
core   +5 more sources

Feasibility and Safety of High‐Dose Proton Re‐Irradiation in Recurrent Pediatric Central Nervous System Tumors: A Single‐Institution Retrospective Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Pediatric central nervous system (CNS) tumors often recur despite multimodality therapy. Although re‐irradiation (re‐RT) has historically been limited by concerns for severe late toxicities, modern techniques have renewed interest in this approach. Proton therapy provides dosimetric advantages that may enable curative re‐treatment with
Jin‐Ho Song   +15 more
wiley   +1 more source

Bw4 ligand and direct T-cell receptor binding induced selection on HLA A and B alleles

open access: yesFrontiers in Immunology, 2023
IntroductionThe HLA region is the hallmark of balancing selection, argued to be driven by the pressure to present a wide variety of viral epitopes. As such selection on the peptide-binding positions has been proposed to drive HLA population genetics. MHC
Reut Levi, Lee Levi, Yoram Louzoun
doaj   +1 more source

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider   +4 more
wiley   +1 more source

The improvement of coordination abilities of young gymnasts aged 7-8 years [PDF]

open access: yesPedagogìka, Psihologìâ ta Mediko-bìologìčnì Problemi Fìzičnogo Vihovannâ ì Sportu, 2012
The article presents the substantive training in gymnastics by young gymnasts aged 7-8 years, the improvement of coordination abilities of gymnasts through simultaneous work with two balls is highlighted.
Mulligildina A.Ya.   +2 more
doaj  

Coprime Factor Reduction of H-infinity Controllers [PDF]

open access: yes, 2003
We consider the efficient solution of the coprime factorization based H infinity controller approximation problems by using frequency-weighted balancing related model reduction approaches.
Varga, Andras
core  

Improved Analysis of Deterministic Load-Balancing Schemes

open access: yes, 2015
We consider the problem of deterministic load balancing of tokens in the discrete model. A set of $n$ processors is connected into a $d$-regular undirected network.
Berenbrink, Petra   +4 more
core   +4 more sources

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