Results 71 to 80 of about 1,542,707 (296)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Security Dilemma of the American Ballistic Missile Defense
Czech Journal of International Relations, 2013 The article deals with the former US President Bush’s plan for the so-called third pillar of the American missile defense system in Poland and the Czech Republic in the context of American-Iranian and American-Russian relations.
Lukáš Kantor
doaj
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Conceptual design and architecture of an informatics solution for smart trading on wholesale energy market in Romania [PDF]
Database Systems Journal, 2017 This paper presents conceptual design and architecture of an informatics solution that aims to implement analytical models for optimization and forecasting the electricity demand and generation, simulation and what if analysis for efficient trading ...
Adela BÂRA +3 more
doaj
Syria in Regional Security System in 2000-2011
Научный диалог, 2017 Syria’s role in regional security in the period of 2000-2011 is discussed. Special attention is paid to the coming to power of Bashar Assad, marked by attempts to soften the confrontation of Syria with regional and extra-regional powers, while ...
M. S. Khodynskaya-Golenichsheva +1 more
doaj +1 more source
Optimal Net-Load Balancing in Smart Grids with High PV Penetration
, 2018 Mitigating Supply-Demand mismatch is critical for smooth power grid operation. Traditionally, load curtailment techniques such as Demand Response (DR) have been used for this purpose.
Aman Saima +3 more
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source