Results 71 to 80 of about 1,513,785 (298)
Multi-objective discrete particle swarm optimisation algorithm for integrated assembly sequence planning and assembly line balancing [PDF]
In assembly optimisation, assembly sequence planning and assembly line balancing have been extensively studied because both activities are directly linked with assembly efficiency that influences the final assembly costs.
Ab Rashid, Mohd Fadzil Faisae +2 more
core +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Balanced and functionally balanced P-groups
Abstract In relation to Itzkowitz’s problem [5], we show that a c-bounded P-group is balanced if and only if it is functionally balanced.We prove that for an arbitrary P-group, being functionally balanced is equivalent to being strongly functionally balanced.
openaire +5 more sources
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Realism vs. Neoliberalism and Constructivism: Main Points of Debate
: Following the collapse of the bipolar world realist approaches were placed under close scrutiny by neoliberals and constructivists. The legacy of the realist school actually became an object of numerous attacks, which were undertaken to demonstrate its
Yury V. Borovsky, Pavel A. Gvozdev
doaj
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Security Dilemma of the American Ballistic Missile Defense
The article deals with the former US President Bush’s plan for the so-called third pillar of the American missile defense system in Poland and the Czech Republic in the context of American-Iranian and American-Russian relations.
Lukáš Kantor
doaj
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Syria in Regional Security System in 2000-2011
Syria’s role in regional security in the period of 2000-2011 is discussed. Special attention is paid to the coming to power of Bashar Assad, marked by attempts to soften the confrontation of Syria with regional and extra-regional powers, while ...
M. S. Khodynskaya-Golenichsheva +1 more
doaj +1 more source

