Results 71 to 80 of about 1,513,785 (298)

Multi-objective discrete particle swarm optimisation algorithm for integrated assembly sequence planning and assembly line balancing [PDF]

open access: yes, 2016
In assembly optimisation, assembly sequence planning and assembly line balancing have been extensively studied because both activities are directly linked with assembly efficiency that influences the final assembly costs.
Ab Rashid, Mohd Fadzil Faisae   +2 more
core   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Balanced and functionally balanced P-groups

open access: yesTopological Algebra and its Applications, 2018
Abstract In relation to Itzkowitz’s problem [5], we show that a c-bounded P-group is balanced if and only if it is functionally balanced.We prove that for an arbitrary P-group, being functionally balanced is equivalent to being strongly functionally balanced.
openaire   +5 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Realism vs. Neoliberalism and Constructivism: Main Points of Debate

open access: yesVestnik MGIMO-Universiteta, 2015
: Following the collapse of the bipolar world realist approaches were placed under close scrutiny by neoliberals and constructivists. The legacy of the realist school actually became an object of numerous attacks, which were undertaken to demonstrate its
Yury V. Borovsky, Pavel A. Gvozdev
doaj  

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Security Dilemma of the American Ballistic Missile Defense

open access: yesCzech Journal of International Relations, 2013
The article deals with the former US President Bush’s plan for the so-called third pillar of the American missile defense system in Poland and the Czech Republic in the context of American-Iranian and American-Russian relations.
Lukáš Kantor
doaj  

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Syria in Regional Security System in 2000-2011

open access: yesНаучный диалог, 2017
Syria’s role in regional security in the period of 2000-2011 is discussed. Special attention is paid to the coming to power of Bashar Assad, marked by attempts to soften the confrontation of Syria with regional and extra-regional powers, while ...
M. S. Khodynskaya-Golenichsheva   +1 more
doaj   +1 more source

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