Results 91 to 100 of about 607,966 (294)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Some preconditioners for systems of linear inequalities

open access: yes, 2013
We show that a combination of two simple preprocessing steps would generally improve the conditioning of a homogeneous system of linear inequalities.
Pena, Javier   +2 more
core   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Links between Main Frequencies of Established Rotating Stall and Rotational Frequencies and/or Blade Passing Frequencies

open access: yesInternational Journal of Rotating Machinery, 2013
The ratios between the main frequency of rotating stall and rotational frequency may be considered in the form of exact ratios of small natural numbers if the pressure signals in compressors during rotating stall include the rotor rotation frequency ...
Yeshayahou Levy   +4 more
doaj   +1 more source

Hybrid numbers with balancing and Lucas balancing hybrid number coefficients

open access: yesCommunications Faculty of Sciences University of Ankara Series A1 Mathematics and Statistics
In this note, we made a connection between hybrid numbers and hybrid balancing, and hybrid Lucas balancing number. Initially, we obtained for these new number recurrence relation, some important relations among new numbers, and Binet's like formula.
Murat Turan   +1 more
openaire   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Factorizations of negatively subscripted balancing and Lucas-balancing numbers

open access: yesBoletim da Sociedade Paranaense de Matemática, 2013
In this paper, we  find some tridigonal matrices whose determinant and permanent are equal to the negatively subscripted balancing and Lucas- balancing numbers. Also using the First and second kind of Chebyshev polynomials, we obtain the factorization of these numbers.  
openaire   +4 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Repdigits as Products of Consecutive Balancing or Lucas-Balancing Numbers

open access: yesThe Fibonacci Quarterly, 2018
Repdigits are natural numbers formed by the repetition of a single digit. In this paper, we explore the presence of repdigits in the product of consecutive balancing or Lucas-balancing numbers.
Rayaguru, Sai Gopal   +1 more
openaire   +2 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

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