Results 141 to 150 of about 949,222 (276)

The Key Technologies and Technological Evolution Mechanisms of Robotic Systems for Fracture Reduction Surgery

open access: yesAdvanced Intelligent Systems, EarlyView.
This review traces three decades of technological evolution in robot‐assisted fracture reduction systems, from early robotic concepts to clinically oriented platforms. Key advances in robotic architecture, navigation, path planning, interaction control, and surgical integration are summarized, while current translational challenges and future ...
Shaolong Kuang   +5 more
wiley   +1 more source

Breakthrough Design of Highly Potent Antivirals Against Wild‐Type HIV‐1 and Lenacapavir‐Resistant M66I Variant

open access: yesAngewandte Chemie, EarlyView.
Lenacapavir, the first‐in‐class drug targeting HIV‐1 capsid, is a breakthrough drug in HIV‐1 treatment and prophylaxis. However, a single M66I mutation confers complete viral resistance to lenacapavir. We report herein the design and synthesis of innovative R2 analogs demonstrating low nM potency against HIV‐1 M66I and excellent pharmacokinetics in ...
Nicolas Jamey   +13 more
wiley   +2 more sources

Bronchoscope Tip Localization With Learned Airway Constraints and an Open Source Simulator

open access: yesAdvanced Intelligent Systems, EarlyView.
BronchoLoc addresses feature‐poor bronchoscopic imaging by combining monocular video with a preoperative CT graph to estimate 3D camera location. A local tracker identifies candidate branches, while a sequence‐aware global module refines the trajectory. Demonstrating sub‐centimeter accuracy across synthetic and phantom datasets, this framework advances
Emanuele Nicotra   +7 more
wiley   +1 more source

Supramolecular Assembly of an Antimicrobial Peptide Into a Pore

open access: yesAngewandte Chemie, EarlyView.
Supramolecular assembly of an AMP is linked to transport across the Staphylococcus aureus membrane. ABSTRACT Antimicrobial peptides (AMPs) have long been ascribed the ability to form pores. These structures, some observed, others inferred, vary in their mechanisms of action, though most are associated with lysis.
Kathyana Deeyagahage   +3 more
wiley   +2 more sources

Immigration detention centers as torturing environments: Ethical reckonings, radical refusals, and implications for a psychology of resistance

open access: yesAmerican Journal of Community Psychology, EarlyView.
Abstract This paper examines psychologists' ethical dilemmas in immigration detention centers. Using critical psychology, border, and detention scholarship, it highlights psychologists' historical complicity in state violence, from the U.S. Enhanced Interrogation Program to current border regimes.
Francesca Esposito   +6 more
wiley   +1 more source

Template‐Encoded Assembly and Adaptive Function in Selenium‐Based Molybdenum Chalcoxide Rings

open access: yesAngewandte Chemie, EarlyView.
External templates write structural information into Se‐containing molybdenum rings, while selenium's softness confers adaptive host–guest behaviour and catalytic responsiveness, an integrated framework for programmable inorganic function. ABSTRACT Controlling both structure and function in inorganic self‐assembly remains a major challenge.
Giulia Pellegrino   +4 more
wiley   +2 more sources

Radical, Not Ionic: The Mechanochemical Zincke Nitration of Phenols

open access: yesAngewandte Chemie, EarlyView.
Mechanochemistry recasts the classical Zincke nitration as an open‐shell process. Liquid‐assisted vibrational milling of phenols with in situ HNO2 delivers direct and ipso nitration across 50 substrates, while atmosphere, NOx‐transfer, EPR and DFT evidence expose a phenoxyl‐radical/NO2 manifold underlying this historically ionic transformation ...
Roberto Scipione   +7 more
wiley   +2 more sources

Ball bearing fault detection using an acoustic based machine learning approach. [PDF]

open access: yesSci Rep
Chandrakala CB   +3 more
europepmc   +1 more source

Making Sense of Standardised Assessment Data: A Response to Snow et al. (2025)

open access: yesAustralian Journal of Social Issues, EarlyView.
ABSTRACT I write in response to the commentary by Snow et al. (2025) on the paper Are Australian students' academic skills declining? Interrogating 25 years of national and international standardised assessment data published in this journal (Larsen 2024).
Sally A. Larsen
wiley   +1 more source

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