Results 221 to 230 of about 662,948 (334)

Hospital-Based Severe Maternal Morbidity Surveillance and Review: A Strategy for Improving Maternity Care in Maryland. [PDF]

Med Care
Creanga AA, Wolfson C, Stierman E, Kramer B, Atlas R, Sheffield J, Burd I, Jones M, Zadzielski E, Aziz K.   +9 more
europepmc   +1 more source

Apathy in Parkinson's Disease: Distinguishing Overlapping Symptoms Via Network Analysis

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Anxiety, fatigue, and excessive daytime sleepiness (EDS) frequently co‐occur in Parkinson's disease (PD) and can influence the clinical determination of apathy. Objective To distinguish patient‐reported apathy from other non‐motor symptoms.
Joseph Seemiller, Abhimanyu Mahajan, Christopher B. Morrow, Joseph F. McGuire, Dawn Bowers, Kelly A. Mills, Gregory M. Pontone   +6 more
wiley   +1 more source

Feasibility and Acceptability of Useful Field of View Cognitive Training in Adolescent Athletes: Pilot Pre-Post Study. [PDF]

JMIR Form Res
Rosenthal ED, Busch TA, Suskauer SJ, Slomine BS, Augustine EF, Akrong ER, Svingos AM.   +6 more
europepmc   +1 more source

A Randomized Controlled Trial of Dual Upper‐Extremity Training [DUET]: Combining Neurologic Music Therapy® with Noninvasive Brain Stimulation for Upper‐Limb Performance in Corticobasal Syndrome

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Corticobasal syndrome (CBS) is a progressive neurodegenerative condition characterized by asymmetric limb rigidity, apraxia, dystonia, and myoclonus, with no approved symptomatic or disease‐modifying drug treatments. Neurologic music therapy (NMT)® employs evidence‐based techniques targeting sensorimotor rehabilitation, and high ...
Kyurim Kang, Isabella Sterner, Shriya Bakhshi, Chris Bedell, Alexander Pantelyat   +4 more
wiley   +1 more source

The RNA-binding protein HuR stabilizes survivin mRNA in human oesophageal epithelial cells. [PDF]

Biochem J
Donahue JM, Chang ET, Xiao L, Wang PY, Rao JN, Turner DJ, Wang JY, Battafarano RJ.   +7 more
europepmc   +1 more source

Developing the Dopamine D3 Receptor (D3R) Antagonist, (R)‐VK4‐116, as a Non‐Opioid Medication for the Treatment of Opioid Use Disorder

Medicinal Research Reviews, EarlyView.
ABSTRACT Opioid use disorder (OUD) remains a major global health challenge, and currently approved treatments (methadone, buprenorphine, and naltrexone) are all opioid receptor‐targeting drugs with limitations in access, adherence, stigma, and use in polysubstance use disorders. Because the dopamine D3 receptor (D3R) is enriched in limbic brain regions
Chia‐Kuei Wu, Yu‐Chih Lin, Junfeng Huang, Bangwei Ding, Pramod Terse, Rahul Nandre, Haksong Jin, Molly Congdon, Kun Shen, Philip Sanderson, Gregory Tawa, Stephanie Mounaud, Marta De Santis, Donald Lo, Elizabeth A. Ottinger, Amy Hauck Newman   +15 more
wiley   +1 more source

Correction: Safety in the Age of Artificial Intelligence: Evaluating Large Language Model Adherence to Antithrombotic Medication and Regional Anesthesia Guidelines. [PDF]

Cureus
Willson CM, Thind BS, Srinivas J, Gupta A.   +3 more
europepmc   +1 more source

Optimizing IMPULSED Acquisition Protocols for Clinical 3T Scanners Through Bayesian Experimental Design

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To optimize diffusion MRI acquisition protocols for Imaging Microstructural Parameters Using Limited Spectrally Edited Diffusion (IMPULSED) model at clinical 3T scanner using Bayesian experimental design, enabling accurate cellular‐scale parameter estimation under realistic scan time and scanner hardware constraints.
Yan Dai, Xun Jia, Todd Aguilera, Kai Jiang, Arely Perez Rodriguez, Isabelle Vanhaezebrouck, Jie Deng   +6 more
wiley   +1 more source

Pre-Antiretroviral Therapy Vertical HIV-1 Transmission Risk in Uganda Varies by Sex of Child and Maternal Viral Subtype. [PDF]

J Infect Dis
Gotthold Z, Epstein-Shuman A, Kigozi G, Lamers SL, Ssempijja V, Quiros G, Martin M, Grabowski MK, Fernandez RE, Chang LW, Galiwango RM, Galiwango RM, Nakigozi G, Reynolds SJ, Scully E, Redd AD, Laeyendecker O, Rakai Health Sciences Program.   +17 more
europepmc   +1 more source

Mesenchymal stem cells as cellular factories for targeted P2X7 blockade after traumatic brain injury

Neuroprotection, EarlyView.
This manuscript presents a novel therapeutic strategy using mesenchymal stem cells (MSCs) engineered as living drug factories to deliver a P2X7‐blocking nanobody for treatment of ischemic stroke. By combining targeted cellular delivery with sustained local immunomodulation, the approach aims to overcome key limitations of systemic biologic ...
Lucia Fadon‐Padilla, Chengyan Chu, Lorissa McDougall, Yajie Liang, Chinmoy Sarkar, Marta Lipinski, Tim Magnus, Miroslaw Janowski, Piotr Walczak   +8 more
wiley   +1 more source