Results 241 to 250 of about 662,948 (334)

Cytokine co-presentation on targeted lipid nanoparticles enhances in vivo T cell engineering. [PDF]

Biomaterials
Patel M, Choy J, Cheng L, Ariail E, Jain M, Shannon SR, Antov D, Cozzone I, Huang X, Cheng M, Li S, Sun J, Yang D, Popov J, Biggs BA, Erb CJ, Chang B, Tian T, Mullaney M, Glenn G, Zhu Y, Wang TH, Green JG, Schneck JP, Spangler JB, Mao HQ.   +25 more
europepmc   +1 more source

Cationic‐Hydrophilic Di‐Block Copolymers: Surface‐Shielded Vectors for Gene Delivery

Journal of Polymer Science, Volume 63, Issue 6, Page 1419-1432, 15 March 2025.
This study develops synthetic polycationic di‐block carriers for nucleic acid (NA) delivery in gene therapy. Consisting of a cationic block and a hydrophilic block, these carriers efficiently form complexes with NAs and shield them with a protective bioinert layer, enhancing stability during circulation in the bloodstream while reducing undesirable ...
Eliška Hrdá, Ladislav Androvič, Marcela Filipová, Michal Pechar, Richard Laga   +4 more
wiley   +1 more source

Hospital Bed Capacity Influences Patient Charges in Outpatient Robotic Total Knee Arthroplasty: A Propensity-Matched Study. [PDF]

Arthroplast Today
Misch M, Katanbaf R, Smitterberg CW, Mont MA, Delanois RE, Nace J.   +5 more
europepmc   +1 more source

Baltimore Lectures On Molecular Dynamics And The Wave Theory Of Light

W. Thomson, B. Kelvin
semanticscholar   +1 more source

GenProb‐PCSM: A Simplified Weighted Germline Score for Prostate Cancer‐Specific Mortality

The Prostate, EarlyView.
ABSTRACT Background We previously developed a tier‐based germline classification using the National Comprehensive Cancer Network (NCCN)‐recommended DNA damage repair (DDR) genes and KLK3 I179T to predict prostate cancer (PCa)‐specific mortality (PCSM).
Jun Wei, Zhuqing Shi, Lucy Lu, John Wang, Julian Xu, Ashley J. Mulford, Huy Tran, Annabelle Ashworth, S. Lilly Zheng, Alan R. Sanders, William B. Issacs, Jun Luo, Brian Helfand, Jim Lu, Jianfeng Xu   +14 more
wiley   +1 more source

Performance characteristics of an electronic medical record alert system to identify hospitalised patients with active hepatitis C virus infection: a cross-sectional analysis from two large academic centres. [PDF]

BMJ Open
Pryal PF, El-Nahal W, Gebo K, Grader-Beck T, Wilson GA, Beatson B, Falade O, Huang S, Berry S.   +8 more
europepmc   +1 more source

Intranasal diamorphine population pharmacokinetics modeling and simulation in pediatric breakthrough pain

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 435-447, March 2025.
Abstract Intranasal diamorphine (IND), approved for managing breakthrough pain in the UK, has been identified as an acceptable alternative offering effective, expedient, and less traumatic analgesia for children. However, the current dose regimen in pediatric populations relies on clinical expertise while the pharmacokinetics properties are poorly ...
Lianjin Cai, Jingchen Zhai, Beihong Ji, Fengyang Han, Taoyu Niu, Luxuan Wang, Junmei Wang   +6 more
wiley   +1 more source

Corrigendum to "PPAR-γ suppresses macrophage senescence and allergic airway inflammation through controlling lipid metabolic pathways" [EBioMedicine 126 (2026) 106226]. [PDF]

EBioMedicine
Gu W, Wan R, Chen Z, Wang W, Xie S, Hao C, Liu G, Wan M, Gao P.   +8 more
europepmc   +1 more source

A sample size analysis of a mathematical model of longitudinal tumor volume and progression‐free survival for Bayesian individual dynamic predictions in recurrent high‐grade glioma

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 495-509, March 2025.
Abstract Patients with recurrent high‐grade glioma (rHGG) have a poor prognosis with median progression‐free survival (PFS) of <7 months. Responses to treatment are heterogenous, suggesting a clinical need for prognostic models. Bayesian data analysis can exploit individual patient follow‐up imaging studies to adaptively predict the risk of progression.
Daniel J. Glazar, Solmaz Sahebjam, Hsiang‐Husan M. Yu, Dung‐Tsa Chen, Menal Bhandari, Heiko Enderling   +5 more
wiley   +1 more source