Reconstitution of Bam Complex-Mediated Assembly of a Trimeric Porin into Proteoliposomes
Porins are a widespread family of homotrimers that represent a substantial fraction of the total protein located in the OM of many proteobacteria. These proteins facilitate the nonspecific diffusion of small molecules across the outer membrane and strongly influence the susceptibility of bacteria to clinically used antibiotics.
Sunyia Hussain +2 more
openaire +3 more sources
Legislation for patient information leaflets in Iran: Focus on lay-friendliness [PDF]
Background: Patient information leaflet (PIL) which accompanies medicinal products and informs patients about dosage, side effects, etc., is known as a tool which empowers patients to be more involved in making decisions related to their medications and ...
Razieh Azari +2 more
doaj +1 more source
Dynamic Simulation of Solar-Powered Heating and Cooling System for an Office Building Using TRNSYS: A Case Study in Kerman [PDF]
Recently, novel techniques have been developed in building industries to use solar heating and cooling systems. The current study develops a Solar-powered Heating and Cooling (SHC) system for an office building in Kerman and assesses the transient ...
Hadi Farzan
doaj +1 more source
Structural basis of outer membrane protein insertion by the BAM complex [PDF]
All Gram-negative bacteria, mitochondria and chloroplasts have outer membrane proteins (OMPs) that perform many fundamental biological processes. The OMPs in Gram-negative bacteria are inserted and folded into the outer membrane by the β-barrel assembly machinery (BAM). The mechanism involved is poorly understood, owing to the absence of a structure of
Gu, Yinghong +10 more
openaire +5 more sources
Overproducing the BAM complex improves secretion of difficult-to-secrete recombinant autotransporter chimeras [PDF]
AbstractMonomeric autotransporters have been used extensively to transport recombinant proteins or protein domains to the cell surface of Gram-negative bacteria amongst others for antigen display. Genetic fusion of such antigens into autotransporters has yielded chimeras that can be used for vaccination purposes.
Trang H. Phan +5 more
openaire +6 more sources
Assembly of Outer Membrane β-Barrel Proteins: the Bam Complex [PDF]
The major class of integral proteins found in the outer membrane (OM) of E. coli and Salmonella adopt a β-barrel conformation (OMPs). OMPs are synthesized in the cytoplasm with a typical signal sequence at the amino terminus, which directs them to the secretion machinery (SecYEG) located in ...
Juliana C, Malinverni, Thomas J, Silhavy
openaire +2 more sources
Surface displacements and source parameters of the 2003 Bam (Iran) earthquake from Envisat advanced synthetic aperture radar imagery [PDF]
The M w 6.6, 26 December 2003 Bam (Iran) earthquake was one of the first earthquakes for which Envisat advanced synthetic aperture radar (ASAR) data were available.
Fielding, E. J. +9 more
core +1 more source
Numerical Analysis of Effective Parameters of Thermoelectric Module by Statistical Method [PDF]
The thermoelectric module is advantageous due to its non generation of toxic waste and versatility across different scales. As a renewable energy source and an alternative to fossil fuels, TEM is recognized as a promising candidate for energy extraction
M. E. Kazemian, M. Khazali
doaj +1 more source
Energy Analysis of a Novel Perforated Cross-flow Solar Air Heaters Integrated with Encapsulated Phase Change Material Units: An Experimental Study [PDF]
This study analyzes the thermal efficiency of a new perforated cross-flow solar air heater (SAH) integrated with encapsulated phase change material (PCM) by using an experimnetal approach.
H. Farzan, M. H. Shahsavari
doaj +1 more source
An In Vitro Assay for Outer Membrane Protein Assembly by the BAM Complex [PDF]
To elucidate the mechanism of a biochemical process it is often essential to reconstitute the reaction in vitro using the minimal set of factors required to drive the reaction to completion. Here, we describe a method to reconstitute the folding and membrane integration of bacterial outer membrane (OM) proteins that have a characteristic β-barrel ...
Giselle, Roman-Hernandez +1 more
openaire +2 more sources

