Results 51 to 60 of about 310,267 (299)

A stepped-impedance bandstop filter with extended upper passbands and improved pass-band reflections

AIP Advances, 2016
A high-performance planar bandstop filter with extended upper passbands and improved pass-band return loss is proposed in this article. In this proposed bandstop filter, a novel three-section stepped-impedance structure is suggested to improve the pass ...
Xiaoying Zuo, Jianguo Yu
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

An Efficient Algorithm to Design Nearly Perfect-Reconstruction Two-Channel Quadrature Mirror Filter Banks

Iranian Journal of Electrical and Electronic Engineering, 2014
In this paper, a novel technique for the design of two-channel Quadrature Mirror Filter (QMF) banks with linear phase in frequency domain is presented. To satisfy the exact reconstruction condition of the filter bank, low-pass prototype filter response ...
S. K. Agrawal, O. P. Sahu
doaj  

Multifunctional current-mode filter with dual-parameter control of the pole frequency

Advances in Electrical and Computer Engineering, 2016
This paper presents a multifunctional current-mode filter with dual-parameter control of the pole frequency. The filter is of the second order, of single-input triple-output (SITO) type and a required type of the response (low pass, inverting band pass,
JERABEK, J., DVORAK, J., SOTNER, R., METIN, B., VRBA, K.   +4 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Compact Muti-Frequency Band-Pass Filters Based on High-Order Mode of Folded Line Spoof Surface Plasmon Polaritons Waveguide

IEEE Access
We proposed a folded line spoof surface plasmonic polaritons (SSPPs) waveguide that allows for efficient and strongly constrained microwave SSPPs transmission.
Siyu Yang, Shuang Liu, Fachun He, Huali Zhu, Liangjing Wang, Dan Lei, Chan Gao, Jun Yan, kShuang Liu   +8 more
doaj   +1 more source

Fully-Differential Multifunctional Electronically Configurable Fractional-Order Filter with Electronically Adjustable Parameters

Elektronika ir Elektrotechnika, 2018
The paper presents a novel solution of a fully-differential 1+α fractional-order filter. The filter can provide low-pass, high-pass, band-pass and band-stop transfer functions without a necessity of a circuitry change (filter is electronically ...
Lukas Langhammer, Roman Sotner, Jan Dvorak, Tomas Dostal   +3 more
doaj   +1 more source

Empirical mode decomposition based on Fourier transform and band-pass filter

International Journal of Naval Architecture and Ocean Engineering, 2019
A novel empirical mode decomposition strategy based on Fourier transform and band-pass filter techniques, contributing to efficient instantaneous vibration analyses, is developed in this study. Two key improvements are proposed.
Zheng-Shou Chen, S. Rhee, Guilin Liu
semanticscholar   +1 more source