Results 81 to 90 of about 629,686 (290)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Band and loop space maintainer--made easy.

Journal of the Indian Society of Pedodontics and Preventive Dentistry, 2004
Space maintainers have been used in Pediatric Dentistry for many years. The use of these appliances, however, in terms of indications, contraindications, design and construction has gained little attention from researchers. This paper highlights the construction of a new technique of fabrication of band and loop space maintainer. The advantages of this
U A, Nayak, J, Loius, R, Sajeev, J, Peter   +3 more
openaire   +1 more source

Loop unitary and phase band topological invariant in generic multiband Chern insulators

Physical Review B
Quench dynamics of topological phases have been studied in the past few years and dynamical topological invariants are formulated in different ways. Yet most of these invariants are limited to minimal systems in which Hamiltonians are expanded by Gamma matrices.
Xi Wu, Ze Yang, Fuxiang Li
openaire   +2 more sources

Quasiparticle anisotropy and pseudogap formation from the weak-coupling renormalization group point of view

, 2004
Using the one-loop functional renormalization group technique we evaluate the self-energy in the weak-coupling regime of the 2D t-t' Hubbard model. At van Hove (vH) band fillings and at low temperatures the quasiparticle weight along the Fermi surface ...
A. A. Katanin, A. P. Kampf, C. Honerkamp, H. J. Vidberg, M. Salmhofer   +4 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Clinical Evaluation of Ghana Shyam's TEFF (Telescopically Expanding Fixed Functional) Space Maintainer Versus Conventional Band and Loop Space Maintainer

Pesquisa Brasileira em Odontopediatria e Clínica Integrada, 2022
Objective: To compare the clinical efficacy of Ghana Shyam's TEFF space maintainer with band and loop space maintainer. Material and Methods: This split-mouth randomized clinical trial was conducted on 20 children (7-9 years), requiring bilateral ...
Narra Venkata Krishna Raviteja, Madu Ghanashyam Prasad   +1 more
doaj  

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

SCExAO as a precursor to an ELT exoplanet direct imaging instrument [PDF]

, 2013
The Subaru Coronagraphic Extreme AO (SCExAO) instrument consists of a high performance Phase Induced Amplitude Apodisation (PIAA) coronagraph combined with an extreme Adaptive Optics (AO) system operating in the near-infrared (H band).
Clergeon, Christophe, Fini, Luca, Garrel, Vincent, Guyon, Olivier, Huby, Elsa, Jovanovic, Nemanja, Kudo, Tomoyuki, Lacour, Sylvestre, Martinache, Frantz, Norris, Barnaby, Perrin, Guy, Singh, Garima, Stewart, Paul, Tuthill, Peter, Vievard, Sebastien   +14 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source