Results 181 to 190 of about 1,120,975 (346)

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Nanoscale Band Gap Modulation and Dual Moiré Superlattices of Hexagonal Boron Nitride Weakly Coupled to Graphite. [PDF]

ACS Nano
J R Costa F, Arribas D, G L Brito T, Cheng TS, Bradford J, Thompson A, Saywell A, Mellor CJ, Beton PH, Novikov SV, Plo J, Gil B, Cassabois G, Zagonel LF, Kuhnke K, Kern K, Rosławska A.   +16 more
europepmc   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Establishing Doping Limits for ZnGa₂O₄ for Ultrawide-Band-Gap Semiconductor Applications. [PDF]

ACS Appl Mater Interfaces
Claes R, Squires AG, Scanlon DO.
europepmc   +1 more source

High-pressure modulation of band gap and microstructure in N-type high-entropy strontium titanate for enhanced thermoelectric performance [PDF]

Xinjian Li, Xiaohuan Luo, Moran Wang, Tu Lyu, Chaohua Zhang, Fusheng Liu, Hongan Ma, Lipeng Hu   +7 more
openalex   +1 more source

Study of Four Element Microstrip Antenna Array Using Patch Type Electromagnetic Band Gap Structure [PDF]

, 2018
K. Prahlada Rao, P. V. Hunagund, R. Váni   +2 more
openalex   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

The optoelectronic, mechanical, and thermoelectric properties of novel wide band gap double perovskites: a first-principles study. [PDF]

Sci Rep
Khan MS, Al-Hmoud M, Nabirye S, Aziz SM.
europepmc   +1 more source

Role of Metals Content in Spinach in Enhancing the Conductivity and Optical Band Gap of Chitosan Films [PDF]

, 2015
Irwana Nainggolan, Devi Shantini, Tulus Ikhsan Nasution, Mohd Nazree Derman   +3 more
openalex   +1 more source