Development of a Lateral Flow Immunoassay Strips for Rapid Antigen Detection of Dabie bandavirus [PDF]
This study reports the development of a point-of-care (POC) serological assay for the detection of the Dabie bandavirus (DBV) infection. Specifically, this assay is based on the principle of lateral flow immunoassay (LFIA) strips. Two monoclonal antibodies against DBV were generated. They showed an optimal pairing. One mAb, named NP-10, was immobilized
Chao Huang +7 more
doaj +5 more sources
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne zoonosis with a high mortality rate in humans. Additionally, dogs are frequently reported to be infected with this disease.
Jiahui Lin +6 more
doaj +3 more sources
Dabie bandavirus (DBV), previously known as severe fever with thrombocytopenia syndrome (SFTS) virus, induces a characteristic thrombocytopenia with a mortality rate ranging from 12% to as high as 30%.
Dokyun Kim, Chih-Jen Lai, Inho Cha
exaly +3 more sources
Safety, Immunogenicity, and Efficacy of a Recombinant Vesicular Stomatitis Virus Vectored Vaccine Against Severe Fever with Thrombocytopenia Syndrome Virus and Heartland Bandavirus [PDF]
Background: Severe fever with thrombocytopenia syndrome virus (SFTSV) is a recently emerged tickborne virus in east Asia with over 18,000 confirmed cases.
Philip Hicks +6 more
doaj +2 more sources
Early plasma exchange for severe fever with thrombocytopenia syndrome (SFTS)-associated encephalopathy and multi-organ dysfunction syndrome (MODS): a case report [PDF]
Background Severe fever with thrombocytopenia syndrome (SFTS) is a tick-borne viral disease caused by Dabie bandavirus, associated with high morbidity and mortality.
Xuebin Wen, Ran Ji, Keqi Dong
doaj +2 more sources
Novel nomograms to predict risk and prognosis in hospitalized patients with severe fever with thrombocytopenia syndrome [PDF]
BackgroundSevere fever with thrombocytopenia syndrome (SFTS) is an emerging and life-threatening infectious disease caused by SFTS virus. Although recent studies have reported the use of nomograms based on demographic and laboratory data to predict the ...
Zhenxing Li, Zhaoru Zhang, Chong Chen
doaj +3 more sources
The public health threat of emerging phenuiviruses [PDF]
Phenuiviruses, a group of arthropod-borne RNA viruses, have the capacity to emerge unexpectedly in human beings, resulting in a spectrum of clinical manifestations, including hemorrhagic disease, hepatitis, shock, encephalitis, congenital abnormalities ...
Liyan Sui +6 more
doaj +2 more sources
Co-Circulation of Tick-Borne Bandaviruses and Orthonairoviruses Across Humans, Livestock, and Rats in Pakistan: Serologic Evidence and Public Health Implications [PDF]
Tick-borne viruses (TBVs) pose significant public health and economic threats. Pakistan has endemic Crimean-Congo hemorrhagic fever virus (CCHFV), but evidence suggests broader TBV circulation.
Muhammad Ammar +16 more
doaj +2 more sources
Diverse virome and potential pathogens in five tick species from metropolis surroundings of Beijing and Tianjin, China [PDF]
Rapid urbanization and dense populations in metropolitan areas increase the risk of tick-borne disease transmission. We profiled 139 RNA libraries of 1697 adult ticks belonging to Haemaphysalis longicornis, Haemaphysalis concinna, Dermacentor silvarum ...
Wan‑Ying Gao +13 more
doaj +2 more sources
Computer-aided designing of a novel multi‑epitope DNA vaccine against severe fever with thrombocytopenia syndrome virus [PDF]
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne viral disease caused by the SFTS virus (Dabie bandavirus), which has become a substantial risk to public health.
Yiran Tao +7 more
doaj +2 more sources

