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Heartland Virus Disease—An Underreported Emerging Infection [PDF]

open access: yesMicroorganisms
First recognized 15 years ago, Heartland virus disease (Heartland) is a tickborne infection contracted from the transmission of Heartland virus (HRTV) through tick bites from the lone star tick (Amblyomma americanum) and potentially other tick species ...
Zygmunt F. Dembek   +3 more
doaj   +6 more sources

A bibliometric and visualized analysis of heartland virus [PDF]

open access: yesFrontiers in Microbiology
BackgroundHeartland virus (HRTV) is an emerging tick-borne bunyavirus first detected in 2009. The purpose of this study was to utilize bibliometric analysis to assess the research trends, key foci, and progress of HRTV.
Huiying Zhang   +3 more
doaj   +6 more sources

Pathogenesis and virulence of Heartland virus [PDF]

open access: yesVirulence
Heartland virus (HRTV), an emerging tick-borne pathogenic bunyavirus, has been a concern since 2012, with an increasing incidence, expanding geographical distribution, and high pathogenicity in the United States.
Kuan Feng   +6 more
doaj   +6 more sources

Heartland Virus Epidemiology, Vector Association, and Disease Potential [PDF]

open access: yesViruses, 2018
First identified in two Missouri farmers exhibiting low white-blood-cell and platelet counts in 2009, Heartland virus (HRTV) is genetically closely related to severe fever with thrombocytopenia syndrome virus (SFTSV), a tick-borne phlebovirus producing ...
Aaron C. Brault   +4 more
doaj   +8 more sources

Heartland Virus in Humans and Ticks, Illinois, USA, 2018–2019 [PDF]

open access: yesEmerging Infectious Diseases, 2020
In 2018, Heartland disease virus infected 2 persons in Illinois, USA. In 2019, ticks were collected at potential tick bite exposure locations and tested for Heartland and Bourbon viruses. A Heartland virus–positive pool of adult male Amblyomma americanum
Holly C. Tuten   +9 more
doaj   +5 more sources

Heartland Virus Transmission, Suffolk County, New York, USA [PDF]

open access: yesEmerging Infectious Diseases, 2021
During 2018, Heartland virus RNA was detected in an Amblyomma americanum tick removed from a resident of Suffolk County, New York, USA. The person showed seroconversion.
Alan P. Dupuis   +14 more
doaj   +5 more sources

Transovarial Transmission of Heartland Virus by Invasive Asian Longhorned Ticks under Laboratory Conditions [PDF]

open access: yesEmerging Infectious Diseases, 2022
We demonstrated experimental acquisition and transmission of Heartland bandavirus by Haemaphysalis longicornis ticks. Virus was detected in tick salivary gland and midgut tissues.
Wilson R. Raney   +2 more
doaj   +5 more sources

Fatal Case of Heartland Virus Disease Acquired in the Mid-Atlantic Region, United States [PDF]

open access: yesEmerging Infectious Diseases, 2023
Heartland virus (HRTV) disease is an emerging tickborne illness in the midwestern and southern United States. We describe a reported fatal case of HRTV infection in the Maryland and Virginia region, states not widely recognized to have human HRTV ...
Sichen Liu   +14 more
doaj   +4 more sources

Pathological and virological findings of type I interferon receptor knockout mice upon experimental infection with Heartland virus [PDF]

open access: yesVirus Research
Heartland virus (HRTV) causes generalized symptoms, severe shock, and multiple organ failure. We previously reported that interferon-α/β receptor knockout (IFNAR-/-) mice infected intraperitoneally with 1 × 107 tissue culture-infective dose (TCID50) of ...
Hikaru Fujii   +18 more
doaj   +4 more sources

The Cap-Snatching SFTSV Endonuclease Domain Is an Antiviral Target [PDF]

open access: yesCell Reports, 2020
Summary: Severe fever with thrombocytopenia syndrome virus (SFTSV) is a tick-borne virus with 12%–30% case mortality rates and is related to the Heartland virus (HRTV) identified in the United States.
Wenjie Wang   +11 more
doaj   +3 more sources

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