A novel tick-borne phlebovirus, closely related to severe fever with thrombocytopenia syndrome virus and Heartland virus, is a potential pathogen. [PDF]
Emerg Microbes Infect, 2018 Tick-borne viral diseases have attracted much attention in recent years because of their increasing incidence and threat to human health. Severe fever with thrombocytopenia syndrome phlebovirus (SFTSV) and Heartland virus (HRTV) were recently identified ...
Shen S +23 more
europepmc +5 more sources
Oropuche virus: A virus present but ignored [PDF]
Revista Mvz Cordoba, 2015 Bunyaviruses are RNA viruses that affect animals and plants; they have five genera and four of them affect humans: Orthobunyavirus, Nairovirus, Phlebovirus and Hantavirus. All of them are Arbovirus, except Hantavirus.
Salim Mattar V., Marco González T.
doaj +6 more sources
Modeling Heartland virus disease in mice and therapeutic intervention with 4′-fluorouridine [PDF]
Journal of VirologyABSTRACT Heartland virus (HRTV) is an emerging tick-borne bandavirus that causes a febrile illness of varying severity in humans, with cases reported in eastern and midwestern regions of the United States. No vaccines or approved therapies are available to prevent or treat HRTV disease.
Craig Martens +2 more
exaly +4 more sources
Secondary hemophagocytic lymphohistiocytosis due to Heartland virus. [PDF]
BMJ Case Rep, 2022 An older man from the mid-Southeastern USA presented with acute onset of fever, fatigue, and non-bloody diarrhoea. There was high suspicion for tick-borne illness given exposure history, clinical presentation and laboratory abnormalities. Despite prompt treatment with doxycycline, the patient clinically worsened.
Ahlers CG +3 more
europepmc +3 more sources
Trends in Tick-Borne Virus Ecology: Vector Incrimination, Focal Distribution, and Reservoir Associations. [PDF]
VirusesTicks are prominent hosts for many viruses that are pathogenic to humans on almost every continent. Despite the documented historical association of ticks with viral disease in humans, clinical case reports are low, likely due to under-recognition of ...
Lange RE, Dupuis AP, Ciota AT.
europepmc +2 more sources
VaccinesBackground: Severe fever with thrombocytopenia syndrome virus (SFTSV) is a recently emerged tickborne virus in east Asia with over 18,000 confirmed cases.
Philip Hicks +6 more
doaj +4 more sources
Focal persistence and phylodynamics of Heartland virus in Georgia. [PDF]
Virus EvolAbstract Heartland virus (HRTV) is an emerging tick-borne virus associated with severe illness in the USA. There are large gaps in knowledge of HRTV diversity, evolution, and transmission due to a paucity of HRTV-positive samples and genome sequences.
Bellman S +15 more
europepmc +3 more sources
Novel Clinical and Pathologic Findings in a Heartland Virus-Associated Death. [PDF]
Clin Infect Dis, 2017 Abstract We describe an investigation into a Heartland virus (HRTV)–associated death in Tennessee with novel clinical and pathologic findings. HRTV can cause rapidly fatal, widely disseminated infection with multisystem organ failure in patients without substantial comorbidities.
Fill MA +9 more
europepmc +4 more sources
Ticks and Tick-Borne Diseases, 2023 Heartland and Bourbon viruses are pathogenic tick-borne viruses putatively transmitted by Amblyomma americanum, an abundant tick species in Missouri. To assess the prevalence of these viruses in ticks, we collected 2778 ticks from eight sampling sites at
Ishmael D. Aziati +9 more
doaj +1 more source
Heartland virus infection in hamsters deficient in type I interferon signaling: Protracted disease course ameliorated by favipiravir [PDF]
Virology, 2017 Brian B Gowen, Saravanan Thangamani
exaly +2 more sources