Heartland virus antagonizes type I and III interferon antiviral signaling by inhibiting phosphorylation and nuclear translocation of STAT2 and STAT1 [PDF]
Journal of Biological Chemistry, 2019 Kuan Feng, Fei Deng, Zhihong Hu
exaly +2 more sources
Dermatological manifestations of tick-borne viral infections found in the United States
Virology Journal, 2022 Tick-borne diseases (TBDs) are bacterial, viral, and parasitic diseases transmitted by ticks. Viral TBDs have increased in prevalence over the last decade with many new pathogenic viruses being discovered.
Ammie Rupani +2 more
doaj +1 more source
Experimental Infection of White-Tailed Deer (Odocoileus virginanus) with Heartland Virus. [PDF]
Am J Trop Med Hyg, 2018 Heartland virus (HRTV) is a phlebovirus suspected to be transmitted by Amblyomma americanum, commonly known as the lone star tick, and reported to cause illness in humans, which is characterized by thrombocytopenia and leukopenia. Heartland virus–reactive antibodies have been detected in a variety of wildlife species including white-tailed deer (WTD ...
Clarke LL, Ruder MG, Mead D, Howerth EW.
europepmc +4 more sources
Lethal Case of Bourbon Virus Leading to Shock and ECMO Utilization. [PDF]
Case Rep Infect DisWe present a lethal case of Bourbon virus infection in a 63‐year‐old Caucasian, diabetic male who was previously in good health. The patient had spent time in the wooded areas of Bourbon County, Kansas, and removed three ticks from his body 5 days prior to presentation.
Mitchell A +6 more
europepmc +2 more sources
Development and Characterization of Monoclonal Antibodies Directed Against the Nucleoprotein of Heartland Virus. [PDF]
Am J Trop Med Hyg, 2015 Heartland virus (HRTV), a phlebovirus first isolated from two Missouri farmers in 2009, has been proposed to be transmitted to humans by the bite of infected Amblyomma americanum ticks. It is closely related to severe fever with thrombocytopenia syndrome virus (SFTSV) from China, another previously unrecognized phlebovirus that has subsequently been ...
Calvert AE, Brault AC.
europepmc +4 more sources
Metagenomic-based Surveillance of Pacific Coast tick Dermacentor occidentalis Identifies Two Novel Bunyaviruses and an Emerging Human Ricksettsial Pathogen. [PDF]
, 2017 An increasing number of emerging tick-borne diseases has been reported in the United States since the 1970s. Using metagenomic next generation sequencing, we detected nucleic acid sequences from 2 novel viruses in the family Bunyaviridae and an emerging ...
Bouquet, Jerome +5 more
core +2 more sources
Heartland Virus Exposure in White-Tailed Deer in the Southeastern United States, 2001-2015. [PDF]
Am J Trop Med Hyg, 2018 Heartland virus (HRTV) is a North American phlebovirus suspected to be transmitted by the lone star tick Amblyomma americanum. White-tailed deer (WTD) have been shown to develop HRTV-neutralizing antibodies following experimental infection. To further define the geographic distribution of HRTV through retrospective sampling of WTD, sera from the WTD ...
Clarke LL +3 more
europepmc +4 more sources
Geographical distribution and pathogenesis of ticks and tick-borne viral diseases
Frontiers in Microbiology, 2023 Ticks are obligatory hematophagous arthropods that harbor and transmit infectious pathogens to humans and animals. Tick species belonging to Amblyomma, Ixodes, Dermacentor, and Hyalomma genera may transmit certain viruses such as Bourbon virus (BRBV ...
Taif Shah +9 more
doaj +1 more source
Immunogenicity and safety of three consecutive production lots of the non replicating smallpox vaccine MVA: A randomised, double blind, placebo controlled phase III trial [PDF]
, 2018 BackgroundModified Vaccinia Ankara (MVA) is a live, viral vaccine under advanced development as a non-replicating smallpox vaccine. A randomised, double-blind, placebo-controlled phase III clinical trial was conducted to demonstrate the humoral ...
Chaplin, Paul +12 more
core +3 more sources
Predicting the potential distribution of Amblyomma americanum (Acari: Ixodidae) infestation in New Zealand, using maximum entropy-based ecological niche modelling [PDF]
, 2020 Publishe
Ganta, RR +5 more
core +1 more source