Generation of Multiple Arbovirus-like Particles Using a Rapid Recombinant Vaccinia Virus Expression Platform [PDF]
Pathogens, 2022 As demonstrated by the 2015 Zika virus outbreak in the Americas, emerging and re-emerging arboviruses are public health threats that warrant research investment for the development of effective prophylactics and therapeutics.
Yuxiang Wang +3 more
doaj +2 more sources
Tick–Virus–Host Interactions at the Cutaneous Interface: The Nidus of Flavivirus Transmission [PDF]
Viruses, 2018 Tick-borne viral diseases continue to emerge in the United States, as clearly evident from the increase in Powassan encephalitis virus, Heartland virus, and Bourbon virus infections.
Meghan E. Hermance +1 more
doaj +2 more sources
Lethal Case of Bourbon Virus Leading to Shock and ECMO Utilization. [PDF]
Case Rep Infect DisWe present a lethal case of Bourbon virus infection in a 63‐year‐old Caucasian, diabetic male who was previously in good health. The patient had spent time in the wooded areas of Bourbon County, Kansas, and removed three ticks from his body 5 days prior to presentation.
Mitchell A +6 more
europepmc +2 more sources
Geographical distribution and pathogenesis of ticks and tick-borne viral diseases [PDF]
Frontiers in Microbiology, 2023 Ticks are obligatory hematophagous arthropods that harbor and transmit infectious pathogens to humans and animals. Tick species belonging to Amblyomma, Ixodes, Dermacentor, and Hyalomma genera may transmit certain viruses such as Bourbon virus (BRBV ...
Taif Shah +9 more
doaj +3 more sources
Secondary hemophagocytic lymphohistiocytosis due to Heartland virus. [PDF]
BMJ Case Rep, 2022 An older man from the mid-Southeastern USA presented with acute onset of fever, fatigue, and non-bloody diarrhoea. There was high suspicion for tick-borne illness given exposure history, clinical presentation and laboratory abnormalities. Despite prompt treatment with doxycycline, the patient clinically worsened.
Ahlers CG +3 more
europepmc +3 more sources
Phleboviruses and the Type I Interferon Response [PDF]
Viruses, 2016 The genus Phlebovirus of the family Bunyaviridae contains a number of emerging virus species which pose a threat to both human and animal health. Most prominent members include Rift Valley fever virus (RVFV), sandfly fever Naples virus (SFNV), sandfly ...
Jennifer Deborah Wuerth +1 more
doaj +2 more sources
Novel Thogotovirus Associated with Febrile Illness and Death, United States, 2014 [PDF]
Emerging Infectious Diseases, 2015 A previously healthy man from eastern Kansas, USA, sought medical care in late spring because of a history of tick bite, fever, and fatigue. The patient had thrombocytopenia and leukopenia and was given doxycycline for a presumed tickborne illness.
Olga I. Kosoy +6 more
doaj +2 more sources
Focal persistence and phylodynamics of Heartland virus in Georgia. [PDF]
Virus EvolAbstract Heartland virus (HRTV) is an emerging tick-borne virus associated with severe illness in the USA. There are large gaps in knowledge of HRTV diversity, evolution, and transmission due to a paucity of HRTV-positive samples and genome sequences.
Bellman S +15 more
europepmc +3 more sources
Novel Clinical and Pathologic Findings in a Heartland Virus-Associated Death. [PDF]
Clin Infect Dis, 2017 Abstract We describe an investigation into a Heartland virus (HRTV)–associated death in Tennessee with novel clinical and pathologic findings. HRTV can cause rapidly fatal, widely disseminated infection with multisystem organ failure in patients without substantial comorbidities.
Fill MA +9 more
europepmc +4 more sources
Heartland virus infection in hamsters deficient in type I interferon signaling: Protracted disease course ameliorated by favipiravir [PDF]
Virology, 2017 Brian Gowen, Saravanan Thangamani
exaly +2 more sources