Heartland virus antagonizes type I and III interferon antiviral signaling by inhibiting phosphorylation and nuclear translocation of STAT2 and STAT1 [PDF]
Journal of Biological Chemistry, 2019 Yun-Jia Ning, Hualin Wang, Zhihong Hu
exaly +2 more sources
Experimental Infection of White-Tailed Deer (Odocoileus virginanus) with Heartland Virus. [PDF]
Am J Trop Med Hyg, 2018 Heartland virus (HRTV) is a phlebovirus suspected to be transmitted by Amblyomma americanum, commonly known as the lone star tick, and reported to cause illness in humans, which is characterized by thrombocytopenia and leukopenia. Heartland virus–reactive antibodies have been detected in a variety of wildlife species including white-tailed deer (WTD ...
Clarke LL, Ruder MG, Mead D, Howerth EW.
europepmc +4 more sources
In 2018, Heartland disease virus infected 2 persons in Illinois, USA. In 2019, ticks were collected at potential tick bite exposure locations and tested for Heartland and Bourbon viruses. A Heartland virus-positive pool of adult male Amblyomma americanum
core +17 more sources
Making place in virus‐free space [PDF]
, 2021 As much a rapidly evolving cultural signifier as a viral materiality, COVID-19 has not biologically penetrated every national border. It is, however, transforming the interpretation, understanding, and experience of place in the absence of infection. One
Carol Farbotko, Farbotko, C
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Development and Characterization of Monoclonal Antibodies Directed Against the Nucleoprotein of Heartland Virus. [PDF]
Am J Trop Med Hyg, 2015 Heartland virus (HRTV), a phlebovirus first isolated from two Missouri farmers in 2009, has been proposed to be transmitted to humans by the bite of infected Amblyomma americanum ticks. It is closely related to severe fever with thrombocytopenia syndrome virus (SFTSV) from China, another previously unrecognized phlebovirus that has subsequently been ...
Calvert AE, Brault AC.
europepmc +4 more sources
Glucosylceramide is essential for Heartland and Dabie bandavirus glycoprotein-induced membrane fusion [PDF]
, 2023 Due to climate changes, there has been a large expansion of emerging tick-borne zoonotic viruses, including Heartland bandavirus (HRTV) and Dabie bandavirus (DBV).
Chih-Jen Lai +10 more
core +3 more sources
Heartland Virus Exposure in White-Tailed Deer in the Southeastern United States, 2001-2015. [PDF]
Am J Trop Med Hyg, 2018 Heartland virus (HRTV) is a North American phlebovirus suspected to be transmitted by the lone star tick Amblyomma americanum. White-tailed deer (WTD) have been shown to develop HRTV-neutralizing antibodies following experimental infection. To further define the geographic distribution of HRTV through retrospective sampling of WTD, sera from the WTD ...
Clarke LL +3 more
europepmc +4 more sources
The Cap-Snatching SFTSV Endonuclease Domain Is an Antiviral Target
Cell Reports, 2020 Summary: Severe fever with thrombocytopenia syndrome virus (SFTSV) is a tick-borne virus with 12%–30% case mortality rates and is related to the Heartland virus (HRTV) identified in the United States.
Wenjie Wang +11 more
doaj +1 more source
Novel Bunyavirus in Domestic and Captive Farmed Animals, Minnesota, USA
Emerging Infectious Diseases, 2013 We tested blood samples from domestic and captive farmed animals in Minnesota, USA, to determine exposure to severe fever with thrombocytopenia syndrome virus and Heartland-like virus.
Zheng Xing +13 more
doaj +1 more source
Uukuniemi Phlebovirus assembly and secretion leave a functional imprint on the Virion Glycome [PDF]
, 2014 Uukuniemi virus (UUKV) is a model system for investigating the genus Phlebovirus of the Bunyaviridae. We report the UUKV glycome, revealing differential processing of the Gn and Gc virion glycoproteins.
Scrivens, JH +23 more
core +1 more source