Novel sialic acid derivatives lock open the 150-loop of an influenza A virus group-1 sialidase [PDF]
This work was supported by the Medical Research Council and the Scottish Funding Council.Influenza virus sialidase has an essential role in the virus’ life cycle.
Russell, Rupert James Martin +35 more
core +1 more source
Cell Culture and Electron Microscopy for Identifying Viruses in Diseases of Unknown Cause
During outbreaks of infectious diseases or in cases of severely ill patients, it is imperative to identify the causative agent. This report describes several events in which virus isolation and identification by electron microscopy were critical to ...
Cynthia S. Goldsmith +17 more
doaj +1 more source
Immune Modulation and Immune-Mediated Pathogenesis of Emerging Tickborne Banyangviruses
In the last decade, the emergence of several, novel tickborne viruses have caused significant disease in humans. Of interest are the tickborne banyangviruses: Severe fever with thrombocytopenia syndrome virus (SFTSV), Heartland virus (HRTV), and Guertu ...
Crystal A. Mendoza +2 more
doaj +1 more source
Interactions between vaccinia virus and sensitized macrophages in vitro [PDF]
The action of peritoneal exudate cells (PEC) from normal and vaccinia virus infected mice on infectious vaccinia virus particles was investigatedin vitro. PEC from immune mice showed a significantly higher infectivity titre reduction (virus clearance, VC)
Kruse, F. +5 more
core +1 more source
In recent years, several newly discovered tick-borne viruses causing a wide spectrum of diseases in humans have been ascribed to the Phlebovirus genus of the Bunyaviridae family.
Veronica V. Rezelj +5 more
doaj +1 more source
Insertion of EGFP into the replicase gene of Semliki Forest virus results in a novel, genetically stable marker virus [PDF]
Alphavirus-based vector and replicon systems have been extensively used experimentally and are likely to be used in human and animal medicine. Whilst marker genes can be inserted easily under the control of a duplicated subgenomic promoter, these ...
Fazakerley, John K +11 more
core +1 more source
Influenza virus activation of the interferon system [PDF]
This study was supported by the Wellcome Trust (grant number 087751/A/08/Z) and the Medical Research Council (grant number G0700848).The host interferon (IFN) response represents one of the first barriers that influenza viruses must surmount in order to ...
Fodor, Ervin +8 more
core +1 more source
Three broad modalities in the natural history of vertically acquired hepatitis C virus infection.
BACKGROUND: Little is known about the natural history of vertically acquired hepatitis C virus (HCV) infection. METHODS: We performed a large, multicenter, prospective study of children born to HCV-infected women in Europe. Children were considered to
European Paediatric Hepatitis C. Virus Network +1 more
core +1 more source
Cellular phosphoinositides and the maturation of bluetongue virus, a non-enveloped capsid virus. [PDF]
BACKGROUND: Bluetongue virus (BTV), a member of Orbivirus genus in the Reoviridae family is a double capsid virus enclosing a genome of 10 double-stranded RNA segments. A non-structural protein of BTV, NS3, which is associated with cellular membranes and
Roy, Polly +3 more
core +1 more source
3D Protein Modeling of L-segment of Heartland virus
3D Protein Modeling of the L-segment of the Heartland virus represents one of the most important problems in computational biology. The present study is designed to build a 3D Structure of heartland virus. It pioneered the field of automated modeling which is used for the 3D Protein Modeling of the L-segment of Heartland virus by the SWISS-MODEL and ...
Hasna Hena Hasna Hena +1 more
openaire +1 more source

