Heartland virus (HRTV) and Severe fever with thrombocytopenia syndrome virus (SFTSV) are closely related phenuiviruses that cause similar diseases in humans. However, animal disease models for both viruses are limited. Here, we first investigated whether
Thomas Bisom +7 more
doaj +1 more source
Cloned defective interfering influenza virus protects ferrets from pandemic 2009 influenza A virus and allows protective immunity to be established [PDF]
Influenza A viruses are a major cause of morbidity and mortality in the human population, causing epidemics in the winter, and occasional worldwide pandemics.
Cheung, Linda +39 more
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Novel Phlebovirus with Zoonotic Potential Isolated from Ticks, Australia
Recently discovered tick-borne phleboviruses have been associated with severe disease and death among persons in Asia and the United States. We report the discovery of a novel tick phlebovirus in Tasmania State, Australia, that is closely related to ...
Jianning Wang +14 more
doaj +1 more source
Low dose influenza virus challenge in the ferret leads to increased virus shedding and greater sensitivity to oseltamivir [PDF]
Ferrets are widely used to study human influenza virus infection. Their airway physiology and cell receptor distribution makes them ideal for the analysis of pathogenesis and virus transmission, and for testing the efficacy of anti-influenza ...
Dove, Brian K. +35 more
core +1 more source
Tomato chocolàte virus: a new plant virus infecting tomato and a proposed member of the genus Torradovirus [PDF]
A new virus was isolated from a tomato plant from Guatemala showing necrotic spots on the bases of the leaves and chocolate-brown patches on the fruits.
Verbeek, M. +11 more
core +1 more source
A novel broad-spectrum treatment for respiratory virus infections : influenza-based defective interfering virus provides protection against pneumovirus infection in vivo [PDF]
Respiratory viruses represent a major clinical burden. Few vaccines and antivirals are available, and the rapid appearance of resistant viruses is a cause for concern.
Edworthy, Nicole Lynn +11 more
core +1 more source
Vaccinia virus replication is not affected by APOBEC3 family members [PDF]
Background: The APOBEC3G protein represents a novel innate defense mechanism against retroviral infection. It facilitates the deamination of the cytosine residues in the single stranded cDNA intermediate during early steps of retroviral infection.
Sutter Gerd +17 more
core +1 more source
Seward CASA Board Development Workshop [PDF]
Agenda from the Seward CASA Board Development Workshop, February 21, 2009, presented by the Heartland Center for Leadership ...
Heartland Center for Leadership Development
core
The Lone Star tick, Amblyomma americanum, salivary factors exacerbate the clinical outcome of Heartland virus disease in a small animal model. [PDF]
Reynolds ES +3 more
europepmc +1 more source

