Results 11 to 20 of about 132 (72)

Virome diversity shaped by genetic evolution and ecological landscape of Haemaphysalis longicornis [PDF]

Microbiome
Background Haemaphysalis longicornis is drawing attentions for its geographic invasion, extending population, and emerging disease threat. However, there are still substantial gaps in our knowledge of viral composition in relation to genetic diversity of
Run-Ze Ye, Yu-Yu Li, Da-Li Xu, Bai-Hui Wang, Xiao-Yang Wang, Ming-Zhu Zhang, Ning Wang, Wan-Ying Gao, Cheng Li, Xiao-Yu Han, Li-Feng Du, Luo-Yuan Xia, Ke Song, Qing Xu, Jing Liu, Nuo Cheng, Ze-Hui Li, Yi-Di Du, Hui-Jun Yu, Xiao-Yu Shi, Jia-Fu Jiang, Yi Sun, Tick Genome and Microbiome Consortium (TIGMIC), Xiao-Ming Cui, Shu-Jun Ding, Lin Zhao, Wu-Chun Cao   +26 more
doaj   +2 more sources

Isolation and Identification of Severe Fever with Thrombocytopenia Syndrome Virus from Farmed Mink in Shandong, China. [PDF]

Transbound Emerg Dis
Severe fever with thrombocytopenia syndrome (SFTS) virus, recently named Bandavirus dabieense, belongs to the genus Bandavirus of family Phenuiviridae, and it causes SFTS in humans with clinical symptoms including fever, thrombocytopenia, gastrointestinal symptoms, and leukocytopenia.
Meng X, Sun J, Yao M, Sun Y, Xu H, Liu C, Chen H, Guo J, Nie X, He L, Zhao Z, Li N, Wang Z, Wang J.   +13 more
europepmc   +2 more sources

The pathogen of SFTS: Bandavirus dabieense phylogenetic analysis and development of an online tool for genotyping

Acta Tropica
Bandavirus dabieense (DBV), the pathogen of SFTS that was included in the WHO's list of priority infectious diseases requiring urgent attention in 2017, belongs to a large and highly diverse class of RNA viruses. Currently, the lack of a unified DBV genotyping standard and the confusion among common genotyping systems cause research result ...
Zhihai Chen, Yuanyuan Zhang, Chuan Song   +2 more
exaly   +3 more sources

Smelly communication between haemaphysalis longicornis and infected hosts with indolic odorants: A case from severe fever with thrombocytopenia syndrome virus. [PDF]

PLoS Neglected Tropical Diseases
ObjectsVector ticks' perception of characteristic odors emitted by infected hosts is key to understand tick's foraging behavior for infected host and design odor-based control strategies for tick-borne diseases.MethodsLaboratory mice knocked out for type
Zhitong Liu, Hao Feng, Xiaohe Liu, Bin Wu, Hong Zhang, Yi Sun, Jiahong Wu, Chunxiao Li, Jiafu Jiang   +8 more
doaj   +2 more sources

Integration of SFTSV Viral Load, Age, and Double-Negative B-Cells as Prognostic Biomarkers for Severe Fever With Thrombocytopenia Syndrome Outcomes. [PDF]

J Immunol Res
Background Severe fever with thrombocytopenia syndrome (SFTS) is a tick‐borne viral illness with high mortality, yet early risk stratification remains challenging. Recent evidence suggests that B‐cell dysregulation contributes to disease severity. Methods A cohort of 168 patients with confirmed SFTS was retrospectively analyzed. Flow cytometry was used
Wei W, Tai Q, Liu H, Chen R, Wang Y, Wang T, Ouyang R, Wu S, Wang F, Hou H.   +9 more
europepmc   +2 more sources

Efficacy of favipiravir treatment for patients with severe fever with thrombocytopenia syndrome assessed with a historical control [PDF]

Antimicrobial Agents and Chemotherapy
Shimojima Masayuki, Daisuke Himeji, Takuo Itô   +2 more
exaly   +2 more sources

Strategic Preparedness of Broad‐Spectrum Antivirals for Rapid Response Towards Next Pandemics

Small Science, Volume 6, Issue 1, January 2026.
Nanoengineered broad‐spectrum antivirals (BSAs) represent a transformative approach to pandemic preparedness. Unlike virus‐specific drugs requiring separate development, BSAs act across multiple viral families through nanoengineering strategies that enhance solubility, bioavailability, and host‐targeted activity.
Sanoj Rejinold N, Geun‐woo Jin, Jin‐Ho Choy   +2 more
wiley   +1 more source

Development of an RT-LAMP−CRISPR/Cas12a assay for rapid and specific detection of Bandavirus dabieense

Journal of Microbiology
Bandavirus dabieense, a single-stranded RNA virus, is the causative agent of severe fever with thrombocytopenia syndrome (SFTS), a disease associated with high fatality rates. Early and accurate diagnosis is essential for improving clinical outcomes, particularly given the limited therapeutic options and high mortality rates associated with SFTS ...
Bo Seung, Song, Yun Hee, Baek, Eun-Ha, Kim, Hyeok-Il, Kwon, Ah-Hyeon, Kim, Si-Hyun, Lee, Yu-Bin, Son, Soo-Hyeon, Kim, Min-Suk, Song, Young Ki, Choi, Su-Jin, Park   +10 more
openaire   +2 more sources

Epidemiological characteristics and viral molecular evolution analysis of severe fever with thrombocytopenia syndrome in Shandong Province, China

Ticks and Tick-Borne Diseases
Characterized by a high mortality rate and a widening global distribution, severe fever with thrombocytopenia syndrome (SFTS) is a tick-borne emerging infectious disease spawned from the Bandavirus dabieense (DBV). Shandong Province emerges as one of the
Xiangjuan Chen, Yuwei Zhang, Qing Duan, Jiaqi Luo, Ruiqing Ma, Xiaomei Zhang, Bo Pang, Chunhong Yin, Xiaolin Jiang   +8 more
doaj   +1 more source

Molecular mechanism of potently neutralizing human monoclonal antibodies against severe fever with thrombocytopenia virus infection

Journal of Virology
Although severe fever with thrombocytopenia syndrome (SFTS) was first described in China in 2009, the case fatality rate remains >40% among patients with multi-organ failure. To date, no antivirals specifically targeting SFTSV have been approved.
Chuansong Quan, Kaixiao Nie, Dezhen Ma, Chao Su, Lianfeng Li, Wenjun Zheng, Chunhong Yin, Yiwen Wang, Peipei Yang, Dingkun Peng, Xin Liu, Weiwei Li, Weixiao Liu, Chao Shan, Jie Zheng, Di Liu, Hong Zhang, Michael J. Carr, George F. Gao, Jianxun Qi, Weifeng Shi   +20 more
doaj   +1 more source