Results 71 to 80 of about 268,877 (281)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

A Scenario-classification Hybrid-based Banding Method for Power Transfer Limits of Critical Inter-corridors

Journal of Modern Power Systems and Clean Energy
To secure power system operations, practical dispatches in industries place a steady power transfer limit on critical inter-corridors, rather than high-dimensional and strong nonlinear stability constraints.
Lidong Yi, Maosheng Ding, Jili Wang, Gao Qiu, Fei Xue, Ji'ang Liu, Yuxiong Huang, Gengfeng Li, Junyong Liu   +8 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Pengajuan Upaya Hukum Banding Terhadap Putusan Bebas Dalam Perkara Tindak Pidana Pemilu Berdasarkan Undang-Undang Nomor 7 Tahun 2017 Tentang Pemilu di Kota Solok Tahun 2019

Unes Journal of Swara Justisia
Pemilu adalah sarana kedaulatan rakyat untuk memilih wakil-wakilnya yang dilaksanakan secara luber dan jurdil. Namun dalam pelaksanannya tidak jarang terjadi pelanggaran.
Ridwan, Ismansyah, Khairul Fahmi
doaj   +1 more source

On the Flow Curve of Colloids Presenting Shear-Induced Phase Transitions [PDF]

, 2007
This work deals with the evaluation of the flow curve of colloidal systems that develop fluid phases with different mechanical properties, namely shear-banding fluids.
Berli, Claudio L. A., Quemada, Daniel
core   +2 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Factors influencing hardenability of steels on the example of grade 42Cr MoS4. Convergence of the results of calculation and experimental methods

Литьë и металлургия, 2019
This article identifies factors influencing hardenability of steels in manufacturing conditions of OJSC « BSW – Management Company of Holding «BMC». The article contains results of a study on dependence of hardenability of steel grade 42CrMoS4 on design ...
S. V. Zakharevich, N. A. Hlazunova
doaj   +1 more source

A dynamical interpretation of flutter instability in a continuous medium

, 2010
Flutter instability in an infinite medium is a form of material instability corresponding to the occurrence of complex conjugate squares of the acceleration wave velocities.
Andrea Piccolroaz, Bertoldi, Bigoni, Bigoni, Bigoni, Bigoni, Bigoni, Bigoni, Bigoni, Bigoni, Bigoni, Davide Bigoni, John R. Willis, Lebedev, Loret, Rice, Willis   +16 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

The Life of Brian … and David: Two Flying‐Foxes' Contribution to Science

Ecology and Evolution
The welfare of free‐living animals in scientific studies must always be in question: do procedures and devices deployed on wildlife negatively affect their welfare?
M. J. Walker, J. A. Welbergen, J. Meade, W. S. J. Boardman, T. Reardon, J. M. Martin, A. McKeown, C. Turbill   +7 more
doaj   +1 more source